Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720417 | 0.84 | NPC1 (0.41) | NPC1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL6990708 | 0.78 | CYP1A1 (0.46) | CYP1A2CYP3A4CYP2C19CYP2C9MKNK2 | |
| SCHEMBL16568841 | 0.76 | CYP1A1 (0.40) | CYP1A2CYP3A4CYP2C9CYP1A1CYP1B1 | |
| SCHEMBL16720427 | 0.73 | PDGFRB (0.45) | PDGFRBPDGFRANPC1KDM4ECYP1A2 | |
| SCHEMBL16720354 | 0.73 | HSD17B1 (0.48) | CYP1A2CYP3A4CYP2C19CYP2C9CLK4 | |
| SCHEMBL16719683 | 0.73 | MAP4K4 (0.41) | PDGFRBPDGFRANPC1KDM4ECYP3A4 | |
| SCHEMBL21643937 | 0.72 | NPC1 (0.54) | PDGFRBPDGFRAAURKATTKAURKB | |
| SCHEMBL16720441 | 0.70 | POLB (0.34) | NPC1ALDH1A1 | |
| SCHEMBL16719421 | 0.69 | MAPK1 (0.51) | MEN1MAPK1KMT2A | |
| SCHEMBL14355082 | 0.69 | NPC1 (0.56) | PDGFRBPDGFRAAURKATTKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |