Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 6/20 | 0.50 |
| ▸ | QPCTL | Q9NXS2 | 5/20 | 0.50 |
| ▸ | PRKCI | P41743 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294109 | 0.79 | QPCT (0.77) | QPCTQPCTLKDM4EALDH1A1 | |
| SCHEMBL27601236 | 0.77 | QPCT (0.41) | QPCTQPCTLPRKCIMAPTKDM4E | |
| SCHEMBL5756878 | 0.75 | QPCT (0.40) | QPCTQPCTLPRKCIMAPTKDM4E | |
| SCHEMBL31143361 | 0.74 | MAPT (0.50) | QPCTQPCTLPRKCIMAPTKDM4E | |
| SCHEMBL6008269 | 0.74 | MAPT (0.50) | QPCTQPCTLPRKCIMAPTKDM4E | |
| SCHEMBL16719752 | 0.74 | NPC1 (0.46) | MAPTAR | |
| SCHEMBL14919896 | 0.72 | IDO1 (0.51) | QPCTQPCTLMAPTALDH1A1LMNA | |
| SCHEMBL29172082 | 0.72 | IDO1 (0.51) | QPCTQPCTLMAPTMEN1POLB | |
| SCHEMBL30848128 | 0.72 | IDO1 (0.51) | QPCTQPCTLMAPTMEN1POLB | |
| SCHEMBL8671614 | 0.72 | QPCT (0.38) | QPCTQPCTLMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |