Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 1.00 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 1.00 |
| ▸ | PREP | P48147 | 13/20 | 0.57 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18175266 | 0.88 | DPP4 (0.92) | DPP4DPP8DPP9PREP | |
| SCHEMBL13287073 | 0.88 | DPP4 (0.92) | DPP4DPP8DPP9PREP | |
| SCHEMBL2742696 | 0.88 | DPP4 (0.92) | DPP4DPP8DPP9PREP | |
| SCHEMBL13882110 | 0.88 | DPP4 (0.92) | DPP4DPP8DPP9PREP | |
| Hydrochloric Acid SCHEMBL6698799 | 0.85 | DPP4 (0.73) | DPP4DPP8DPP9PREPDPP7 | |
| SCHEMBL2555136 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP9PREP | |
| SCHEMBL646974 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP9PREP | |
| SCHEMBL14641775 | 0.84 | DPP4 (0.81) | DPP4DPP8DPP9PREP | |
| SCHEMBL8021363 | 0.84 | DPP4 (0.81) | DPP4DPP8DPP9PREP | |
| SCHEMBL20162036 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP9PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611782-A1 | SALTS OF LORCASERIN WITH OPTICALLY ACTIVE ACIDS | Arena Pharmaceuticals, Inc. (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012170702-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012030938-A1 | SALTS OF LORCASERIN WITH OPTICALLY ACTIVE ACIDS | ARENA PHARMACEUTICALS, INC. (US) | 2012-03-08 | — | — | WO | disclosed |