Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 17/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 13/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16721990 | 0.86 | TSHR (0.44) | — | |
| SCHEMBL16722391 | 0.85 | S1PR5 (0.54) | S1PR5S1PR1S1PR3HTR2AKCNH2 | |
| SCHEMBL16722331 | 0.84 | S1PR5 (0.59) | S1PR5S1PR1S1PR3HTR2AKCNH2 | |
| SCHEMBL16722437 | 0.83 | S1PR5 (0.54) | S1PR5S1PR1S1PR3 | |
| SCHEMBL16722188 | 0.83 | S1PR5 (0.56) | S1PR5S1PR1S1PR3HTR2AKCNH2 | |
| SCHEMBL16722661 | 0.83 | S1PR5 (0.56) | S1PR5S1PR1S1PR3HTR2AKCNH2 | |
| SCHEMBL16722681 | 0.81 | S1PR5 (0.56) | S1PR5S1PR1S1PR3 | |
| SCHEMBL16722623 | 0.80 | S1PR1 (0.52) | S1PR5S1PR1S1PR3HTR2AKCNH2 | |
| SCHEMBL16719292 | 0.78 | LTA4H (0.42) | S1PR5S1PR1S1PR3 | |
| SCHEMBL16722607 | 0.78 | S1PR5 (0.54) | S1PR5S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073547-A1 | DISUBSTITUTED PHENOXY AZETIDINE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-05-21 | — | — | WO | claimed |
| WO-2015073547-A1 | DISUBSTITUTED PHENOXY AZETIDINE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-05-21 | — | — | WO | disclosed |
| WO-2015073547-A1 | DISUBSTITUTED PHENOXY AZETIDINE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-05-21 | — | — | WO | disclosed |