Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2829221 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP2A6CYP1A2CYP3A4KDM4E | |
| SCHEMBL29896037 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP2A6CYP1A2CYP3A4KDM4E | |
| SCHEMBL10297586 | 0.81 | ALDH1A1 (0.41) | ALDH1A1CYP2A6CYP1A2CYP3A4KDM4E | |
| SCHEMBL28946087 | 0.81 | LMNA (0.44) | ALDH1A1CYP1A2CYP3A4KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL10942983 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP2A6CYP1A2CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL30967433 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP2A6CYP1A2CYP3A4KDM4E | |
| SCHEMBL14749003 | 0.78 | — | — | |
| Ethyne SCHEMBL17596309 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CYP2A6CYP1A2CYP3A4KDM4E | |
| SCHEMBL576332 | 0.75 | HPGD (0.55) | ALDH1A1CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25574416 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11007275-B2 | Cryptophycin antibody conjugates for the treatment of cancer | SANOFI (FR) | 2021-05-18 | — | — | US | disclosed |
| US-20150139901-A1 | Radioactive Rhodium Complexes, Preparation Methods and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE (INSERM) (FR) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11007275-B2 | Cryptophycin antibody conjugates for the treatment of cancer | XPOT, CHMP4B, XPO5 | ALDH1A1 2273/4885CYP2A6 1270/4885CYP1A2 1293/4885 |
| US-20150139901-A1 | Radioactive Rhodium Complexes, Preparation Methods and Uses Thereof | RAB35, MRPL21, MRPS35 | ALDH1A1 4118/4885CYP2A6 2361/4885CYP1A2 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.