⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469683 | 0.93 | — | — | |
| SCHEMBL4499284 | 0.74 | — | — | |
| SCHEMBL2057105 | 0.74 | — | — | |
| SCHEMBL131101 | 0.72 | — | — | |
| SCHEMBL23392480 | 0.69 | — | — | |
| SCHEMBL905422 | 0.67 | — | — | |
| SCHEMBL7263952 | 0.66 | — | — | |
| SCHEMBL4579554 | 0.65 | — | — | |
| SCHEMBL352075 | 0.64 | CA12 (0.33) | — | |
| SCHEMBL171608 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294118-A1 | WATER SOLUBLE FLUORESCENT COMPOUNDS | BIOSEARCH TECHNOLOGIES, INC. (US) | 2011-12-01 | — | — | US | disclosed |
| US-8030096-B2 | Water-soluble rhodamine dyes conjugates | APPLIED BIOSYSTEMS LLC (US) | 2011-10-04 | — | — | US | disclosed |
| US-20110081688-A1 | Water-Soluble Rhodamine Dyes Conjugates | Life Technologies Corporation (US) | 2011-04-07 | — | — | US | disclosed |
| US-7906629-B2 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-03-15 | — | — | US | disclosed |
| US-7868157-B2 | low non-specific binding, photostable, ease of chemical modification to permit tuning of absorption and emission wavelengths and resistance to the formation of dimers; 1-(5-carboxy-pentyl)-2-[5-(1-ethyl-3,3-dimethyl-5-phosphono-1,3-dihydro-indol-2-ylidene)-penta-1,3-dienyl]-3,3-dimethyl-3H-indolium | BIOSEARCH TECHNOLOGIES, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-7795042-B2 | Water-soluble rhodamine dye conjugates | APPLIED BIOSYSTEMS, LLC (US) | 2010-09-14 | — | — | US | disclosed |
| US-7649085-B2 | Saquinavir conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20090305433-A1 | Water-Soluble Rhodamine Dye Conjugates | APPLIED BIOSYSTEMS INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-7592188-B2 | environmentally sensitive fluorescent dye covalently linked to a binding domain which has specific affinity for a target molecule; fluorescence resonance energy transfer; detecting changes in the binding, conformational change; detecting human immunodeficiency virus | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-09-22 | — | — | US | disclosed |
| US-7569678-B2 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-6372907-B1 | LABELLED RHODAMINE DYE-POLYPEPTIDE CONJUGATE, OR SALT THEREOF, COMPRISING RHODAMINE-TYPE PARENT XANTHENE RING SUBSTITUTED AT XANTHENE C-9 CARBON WITH SUBSTITUTED PHENYL RING | APPTERA CORPORATION | 2002-04-16 | — | — | US | disclosed |
| EP-1141137-A1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | Applera Corporation (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001051487-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | PFIZER PRODUCTS INC. (US) | 2001-07-19 | — | — | WO | disclosed |
| EP-1102762-A2 | 2-SUBSTITUTED-1-PIPERIDYL BENZIMIDAZOLE COMPOUNDS AS ORL1-RECEPTOR AGONISTS | PFIZER INC. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2001032783-A1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | APPLERA CORPORATION (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6191278-B1 | COMPRISING A RHODAMINE-TYPE PARENT RING HAVING ATTACHED TO THE XANTHENE C9 CARBON A PHENYL GROUP THAT IS SUBSTITUTED WITH CARBOXY OR SULFONATE GROUP, ONE TO THREE AMINOPYRIDINIUM GROUPS AND AN ALKYL- OR ARYLTHIO, AND OPTIONALLY OTHER GROUPS | PE CORPORATION | 2001-02-20 | — | — | US | disclosed |
| WO-2000008013-A2 | 2-SUBSTITUTED-1-PIPERIDYL BENZIMIDAZOLE COMPOUNDS AS ORL1-RECEPTOR AGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 2000-02-17 | — | — | WO | disclosed |
| EP-0977766-A1 | GLYCOCONJUGATED FLUORESCENT LABELING REAGENTS | CARNEGIE-MELLON UNIVERSITY (US) | 2000-02-09 | — | — | EP | disclosed |
| US-5877310-A | INCUBATING A TARGET MATERIAL HAVING A FUNCTIONAL GROUP AND A GLYCOCONJUGATED FLUORESCENT COMPOUND OF A FLUOROPHORE,A SUGAR AND A REACTIVE GROUP FOR A PERIOD OF TIME SUFFICIENT TO REACT REACTIVE GROUP WITH FUNCTIONAL GROUP OF THE TARGET | CARNEGIE MELLON UNIVERSITY (US) | 1999-03-02 | — | — | US | disclosed |
| WO-1998049176-A1 | GLYCOCONJUGATED FLUORESCENT LABELING REAGENTS | CARNEGIE MELLON UNIVERSITY (US) | 1998-11-05 | — | — | WO | disclosed |