⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672599 | 0.93 | — | — | |
| SCHEMBL7263952 | 0.70 | — | — | |
| SCHEMBL352075 | 0.69 | CA12 (0.33) | — | |
| SCHEMBL171608 | 0.68 | — | — | |
| SCHEMBL4499284 | 0.66 | — | — | |
| SCHEMBL131101 | 0.63 | — | — | |
| SCHEMBL2248281 | 0.62 | — | — | |
| SCHEMBL8736481 | 0.62 | ALDH1A1 (0.38) | — | |
| SCHEMBL5469680 | 0.62 | — | — | |
| SCHEMBL6661449 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983272-B1 | A NEW CLASS OF BENZOPORPHYRIN DERIVATIVE PHOTOACTIVE COMPOUNDS | UNIV BRITISH COLUMBIA (CA) | 2003-10-29 | — | — | EP | claimed |
| US-7166715-B2 | Nitro-substituted non-fluorescent asymmetric cyanine dye compounds | APPLERA CORPORATION (US) | 2007-01-23 | — | — | US | disclosed |
| US-20050009058-A1 | As quencher in reporter-quencher energy-transfer dye pair for nucleic acid hybridization assays; hairpin motif | APPLERA CORPORATION (US) | 2005-01-13 | — | — | US | disclosed |
| US-6750024-B2 | USEFUL AS QUENCHERS IN A REPORTER-QUENCHER ENERGY-TRANSFER DYE PAIR | APPLERA CORPORATION | 2004-06-15 | — | — | US | disclosed |
| US-20030207305-A1 | Nitro-substituted non-fluorescent asymmetric cyanine dye compounds | APPLERA CORPORATION (US) | 2003-11-06 | — | — | US | disclosed |
| US-6541618-B1 | Detecting hybrids | APPLERA CORPORATION | 2003-04-01 | — | — | US | disclosed |
| EP-1049744-B1 | ASYMMETRIC CYANINE DYE QUENCHERS | PE CORP NY (US) | 2002-01-23 | — | — | EP | disclosed |
| EP-1049744-A1 | ASYMMETRIC CYANINE DYE QUENCHERS | PE Corporation (NY) (US) | 2000-11-08 | — | — | EP | disclosed |
| US-6080868-A | AS A QUENCHER IN A REPORTER-QUENCHER ENERGY-TRANSFER DYE PAIR FOR NUCLEIC ACID HYBRIDIZATION ASSAYS | THE PERKIN-ELMER CORPORATION (US) | 2000-06-27 | — | — | US | disclosed |
| WO-1999037717-A1 | ASYMMETRIC CYANINE DYE QUENCHERS | THE PERKIN-ELMER CORPORATION (US) | 1999-07-29 | — | — | WO | disclosed |