⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2057105 | 1.00 | — | — | |
| SCHEMBL7263952 | 0.93 | — | — | |
| SCHEMBL1672599 | 0.74 | — | — | |
| SCHEMBL131101 | 0.72 | — | — | |
| SCHEMBL23392480 | 0.69 | — | — | |
| SCHEMBL5469683 | 0.66 | — | — | |
| SCHEMBL29391493 | 0.64 | — | — | |
| SCHEMBL171608 | 0.63 | — | — | |
| SCHEMBL4579554 | 0.61 | — | — | |
| SCHEMBL6661449 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592188-B2 | environmentally sensitive fluorescent dye covalently linked to a binding domain which has specific affinity for a target molecule; fluorescence resonance energy transfer; detecting changes in the binding, conformational change; detecting human immunodeficiency virus | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-09-22 | — | — | US | disclosed |
| EP-1735453-A2 | FLUORESCENT SIGNAL EMITTING LIVE CELL BIOSENSOR MOLECULES AND DYES FOR DETECTION AND QUANTIFICATION OF PROTEIN ACTIVITIES | The Scripps Research Institute (US) | 2006-12-27 | — | — | EP | disclosed |
| US-20060029946-A1 | Live cell biosensors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-02-09 | — | — | US | disclosed |
| WO-2005088308-A2 | FLUORESCENT SIGNAL EMITTING LIVE CELL BIOSENSOR MOLECULES AND DYES FOR DETECTION AND QUANTIFICATION OF PROTEIN ACTIVITIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2004013139-A2 | PROCESS FOR PREPARING 7-AZAINDOLES | EISAI CO., LTD (JP) | 2004-02-12 | — | — | WO | disclosed |
| EP-1244656-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | Pfizer Products Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001051487-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | PFIZER PRODUCTS INC. (US) | 2001-07-19 | — | — | WO | disclosed |
| EP-1102762-A2 | 2-SUBSTITUTED-1-PIPERIDYL BENZIMIDAZOLE COMPOUNDS AS ORL1-RECEPTOR AGONISTS | PFIZER INC. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000008013-A2 | 2-SUBSTITUTED-1-PIPERIDYL BENZIMIDAZOLE COMPOUNDS AS ORL1-RECEPTOR AGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 2000-02-17 | — | — | WO | disclosed |
| EP-0977766-A1 | GLYCOCONJUGATED FLUORESCENT LABELING REAGENTS | CARNEGIE-MELLON UNIVERSITY (US) | 2000-02-09 | — | — | EP | disclosed |
| US-5877310-A | INCUBATING A TARGET MATERIAL HAVING A FUNCTIONAL GROUP AND A GLYCOCONJUGATED FLUORESCENT COMPOUND OF A FLUOROPHORE,A SUGAR AND A REACTIVE GROUP FOR A PERIOD OF TIME SUFFICIENT TO REACT REACTIVE GROUP WITH FUNCTIONAL GROUP OF THE TARGET | CARNEGIE MELLON UNIVERSITY (US) | 1999-03-02 | — | — | US | disclosed |
| WO-1998049176-A1 | GLYCOCONJUGATED FLUORESCENT LABELING REAGENTS | CARNEGIE MELLON UNIVERSITY (US) | 1998-11-05 | — | — | WO | disclosed |