Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | HK2 | P52789 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21073965 | 1.00 | ADORA1 (0.40) | ADORA1ADORA3ADORA2AADORA2BLGALS9 | |
| SCHEMBL25495898 | 1.00 | ADORA1 (0.40) | ADORA1ADORA3ADORA2AADORA2BLGALS9 | |
| SCHEMBL25495889 | 0.85 | LGALS9 (0.35) | ADORA1ADORA3ADORA2AADORA2BLGALS9 | |
| SCHEMBL16731210 | 0.84 | GALR3 (0.39) | ADORA3ADORA2ALGALS9LGALS1LGALS3 | |
| SCHEMBL18521765 | 0.84 | GALR3 (0.39) | ADORA3ADORA2ALGALS9LGALS1LGALS3 | |
| SCHEMBL25495888 | 0.78 | PTPN1 (0.32) | LMNAALDH1A1RAB9ATSHR | |
| SCHEMBL25495879 | 0.78 | — | — | |
| SCHEMBL21073968 | 0.78 | — | — | |
| SCHEMBL20243833 | 0.76 | ABL1 (0.35) | ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25495855 | 0.75 | HIF1A (0.48) | ADORA1ADORA3ADORA2AADORA2BADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994604-B2 | Pyrazolotriazolyl nucleoside analogues and oligonucleotides comprising them | BIO-LAB LTD. (IL) | 2018-06-12 | — | — | US | disclosed |
| US-20150141490-A1 | PYRAZOLOTRIAZOLYL NUCLEOSIDE ANALOGUES AND OLIGONUCLEOTIDES COMPRISING THEM | BIO-LAB LTD. (IL) | 2015-05-21 | — | — | US | disclosed |
| US-20150141490-A1 | PYRAZOLOTRIAZOLYL NUCLEOSIDE ANALOGUES AND OLIGONUCLEOTIDES COMPRISING THEM | BIO-LAB LTD. (IL) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141490-A1 | PYRAZOLOTRIAZOLYL NUCLEOSIDE ANALOGUES AND OLIGONUCLEOTIDES COMPRISING THEM | NT5C2, TK2, DUT | ADORA1 1066/4885ADORA3 466/4885ADORA2A 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.