Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | MTTP | P55157 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13058919 | 0.81 | RAB9A (0.59) | TSHRRAB9AALDH1A1LMNANAAA | |
| SCHEMBL21101395 | 0.79 | PREP (0.68) | RAB9A | |
| SCHEMBL1442608 | 0.78 | RAB9A (0.70) | TSHRRAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL16381886 | 0.77 | RAB9A (0.58) | RAB9AALDH1A1KMT2ANPC1POLB | |
| SCHEMBL1945575 | 0.77 | POLB (0.52) | TSHRRAB9AKMT2APOLBSMN1; SMN2 | |
| SCHEMBL3275319 | 0.77 | RAB9A (0.68) | TSHRRAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL10337975 | 0.77 | CHRNB2 (0.58) | ALDH1A1LMNACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8289085 | 0.76 | RAB9A (0.53) | RAB9AALDH1A1LMNAKMT2ANPC1 | |
| SCHEMBL8286857 | 0.76 | RAB9A (0.68) | RAB9AALDH1A1NPC1POLB | |
| SCHEMBL5067725 | 0.76 | HTT (0.57) | TSHRRECQLALDH1A1LMNACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385948-A1 | FUSED THIAZOLO AND OXAZOLO PYRIMIDINONES | Torrent Pharmaceuticals Limited (IN) | 2011-11-16 | — | — | EP | disclosed |
| WO-2011045811-A1 | FUSED THIAZOLO AND OXAZOLO PYRIMIDINONES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-21 | — | — | WO | disclosed |