Methyl Deoxycholate

Methyl Deoxycholate

SCHEMBL16728282

COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)C3CC(O)[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
USP2 O75604 2/20 1.00
LMNA P02545 1/20 1.00
MAPK1 P28482 1/20 1.00
GPBAR1 Q8TDU6 8/20 0.80
SLC10A2 Q12908 2/20 0.80
TBXA2R P21731 1/20 0.80
PDE3A Q14432 1/20 0.80
NR1H4 Q96RI1 1/20 0.80
CYP2C9 P11712 1/20 0.79
HIF1A Q16665 1/20 0.79
VDR P11473 1/20 0.79
CYP3A4 P08684 2/20 0.75
SLCO1B3 Q9NPD5 1/20 0.75
SLCO1B1 Q9Y6L6 1/20 0.75
ABCC4 O15439 1/20 0.70
CA1 P00915 6/20 0.67
CA2 P00918 6/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Deoxycholate SCHEMBL13851607 1.00 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL17974551 1.00 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL14668286 1.00 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL19682166 1.00 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL19566301 1.00 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL16728288 1.00 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL21846440 1.00 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL21904594 1.00 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL21283695 1.00 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL13260288 1.00 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150141679-A1 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID KYTHERA BIOPHARMACEUTICALS, INC. (US) 2015-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141679-A1 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID HSD11B1, HSD17B7, HSD11B2 MAPT 3803/4885MEN1 1813/4885KMT2A 2262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.