SCHEMBL16728552

SCHEMBL16728552

COC(=O)CCCC(N)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
LMNA P02545 2/20 0.46
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.43
KMT2A Q03164 1/20 0.43
KDM4E B2RXH2 1/20 0.42
PPARG P37231 1/20 0.41
AKT1 P31749 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21161250 0.90 CA12 (0.48) CA12CA7CA9CA14LMNA
SCHEMBL6345408 0.90 CA12 (0.48) CA12CA7CA9CA14LMNA
Hydrochloric Acid SCHEMBL27412896 0.89 CA12 (0.47) CA12CA7CA9CA14LMNA
SCHEMBL3713253 0.83 PRSS1 (0.51) LMNAALDH1A1KMT2AKDM4EHSD17B10
SCHEMBL13064827 0.82 CA12 (0.50) CA12CA7CA9CA14LMNA
SCHEMBL671557 0.81 LTA4H (0.49) TSHRALDH1A1CYP1A2CYP2D6MAPK1
SCHEMBL10356118 0.81 LTA4H (0.49) TSHRALDH1A1CYP1A2CYP2D6MAPK1
SCHEMBL27477537 0.81 LTA4H (0.49) TSHRALDH1A1CYP1A2CYP2D6MAPK1
SCHEMBL318685 0.81 CA12 (0.46) CA12CA7CA9CA14LMNA
SCHEMBL27764678 0.81 CA12 (0.46) CA12CA7CA9CA14LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150136233-A1 ORGANIC PHOTOVOLTAIC DEVICES COMPRISING FULLERENES AND DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-05-21 US disclosed