Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816427 | 0.91 | IDO1 (0.66) | ALDH1A1IDO1LMNAGAA | |
| SCHEMBL1192659 | 0.87 | ALDH1A1 (0.63) | ALDH1A1RORCSMN1; SMN2BLMSLC22A12 | |
| SCHEMBL307278 | 0.86 | IDO1 (0.62) | ALDH1A1IDO1LMNAGAAAR | |
| SCHEMBL16722682 | 0.85 | IDO1 (0.60) | ALDH1A1IDO1LMNAGAARORC | |
| SCHEMBL7234787 | 0.85 | RORC (0.53) | ALDH1A1RORCSMN1; SMN2 | |
| SCHEMBL202348 | 0.84 | IDO1 (0.54) | ALDH1A1IDO1LMNAGAARORC | |
| SCHEMBL6816436 | 0.84 | ALDH1A1 (0.48) | ALDH1A1IDO1LMNAGAARORC | |
| SCHEMBL8351343 | 0.84 | ALDH1A1 (0.79) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12050119 | 0.81 | AR (0.58) | IDO1AR | |
| SCHEMBL13909401 | 0.81 | IDO1 (0.54) | ALDH1A1IDO1LMNAGAARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147278-A1 | COMPOUND FOR TREATING BREAST CANCER AND PROGESTIN-DEPENDENT CONDITIONS | University of Tennessee Research Foundation (US) | 2017-03-29 | — | — | EP | disclosed |
| WO-2015073767-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |