Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.31 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16700427 | 0.77 | KMT2A (0.37) | KMT2AALDH1A1SMN1; SMN2HPGDPLAT | |
| SCHEMBL16700630 | 0.71 | KMT2A (0.35) | KMT2AALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL16711267 | 0.71 | PLAT (0.34) | KMT2AALDH1A1SMN1; SMN2HPGDPLAT | |
| SCHEMBL16700456 | 0.71 | ADORA1 (0.36) | KMT2AALDH1A1SMN1; SMN2NPSR1GAA | |
| SCHEMBL16701033 | 0.70 | POLB (0.34) | KMT2AALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL16699755 | 0.69 | PLAT (0.34) | KMT2AALDH1A1SMN1; SMN2PLATGRK6 | |
| SCHEMBL16699886 | 0.69 | KMT2A (0.35) | KMT2AALDH1A1PLATMAPTPOLB | |
| SCHEMBL16699032 | 0.69 | ADORA3 (0.37) | KMT2AALDH1A1TSHRHPGDPLAT | |
| SCHEMBL16699701 | 0.66 | ALDH1A1 (0.31) | ALDH1A1POLBGAA | |
| SCHEMBL20748890 | 0.65 | PLAT (0.39) | KMT2AALDH1A1SMN1; SMN2HPGDPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073767-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |