Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 7/20 | 0.40 |
| ▸ | EED | O75530 | 2/20 | 0.37 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.37 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.37 |
| ▸ | AEBP2 | Q6ZN18 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16744313 | 0.89 | EED (0.47) | KDM4EPKMALDH1A1HSD17B10HPGD | |
| SCHEMBL17885416 | 0.82 | EZH2 (0.48) | KDM4EPKMEZH2EEDRBBP4 | |
| SCHEMBL15174113 | 0.80 | EED (0.46) | KDM4EPKMEZH2EEDRBBP4 | |
| SCHEMBL17880825 | 0.78 | EZH2 (0.45) | KDM4EPKMALDH1A1HSD17B10HPGD | |
| SCHEMBL16377039 | 0.77 | EZH2 (0.45) | KDM4EPKMALDH1A1HSD17B10HPGD | |
| SCHEMBL2594097 | 0.77 | KDM4E (0.46) | KDM4EPKMALDH1A1HSD17B10HPGD | |
| SCHEMBL18455533 | 0.76 | HPGD (0.53) | KDM4EPKMALDH1A1HSD17B10HPGD | |
| SCHEMBL14917611 | 0.75 | GRIN2D (0.46) | KDM4EPKMALDH1A1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL2591197 | 0.75 | KDM4E (0.45) | KDM4EPKMALDH1A1HSD17B10HPGD | |
| SCHEMBL21156095 | 0.75 | EZH2 (0.41) | KDM4EPKMALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150141436-A1 | INDOLES | KIDS2, INC. | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141436-A1 | INDOLES | IDO1, IDO2, INMT | KDM4E 1312/4885PKM 3097/4885ALDH1A1 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.