Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 2/20 | 0.47 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.47 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.47 |
| ▸ | AEBP2 | Q6ZN18 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | EZH2 | Q15910 | 15/20 | 0.43 |
| ▸ | EZH1 | Q92800 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16728899 | 0.89 | KDM4E (0.42) | EEDRBBP4SUZ12AEBP2KDM4E | |
| SCHEMBL20991832 | 0.82 | KDM4E (0.53) | EEDRBBP4SUZ12AEBP2KDM4E | |
| SCHEMBL17970524 | 0.81 | EED (0.45) | EEDRBBP4SUZ12AEBP2KDM4E | |
| SCHEMBL1694684 | 0.79 | KDM4E (0.50) | EEDRBBP4SUZ12AEBP2KDM4E | |
| SCHEMBL17885416 | 0.78 | EZH2 (0.48) | EEDRBBP4SUZ12AEBP2KDM4E | |
| SCHEMBL17734330 | 0.78 | KDM4E (0.47) | EEDRBBP4SUZ12AEBP2KDM4E | |
| Hydrochloric Acid SCHEMBL13280706 | 0.78 | KDM4E (0.49) | EEDRBBP4SUZ12AEBP2KDM4E | |
| SCHEMBL17880825 | 0.74 | EZH2 (0.45) | EEDRBBP4SUZ12AEBP2KDM4E | |
| SCHEMBL16377039 | 0.73 | EZH2 (0.45) | EEDRBBP4SUZ12AEBP2KDM4E | |
| SCHEMBL17713635 | 0.72 | EED (0.57) | EEDRBBP4SUZ12AEBP2EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015077194-A1 | INHIBITORS OF LYSINE METHYL TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-28 | — | — | WO | disclosed |