Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17772168 | 0.85 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1MEN1 | |
| SCHEMBL1806573 | 0.85 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1MEN1 | |
| SCHEMBL15585678 | 0.85 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1MEN1 | |
| SCHEMBL204043 | 0.85 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1MEN1 | |
| SCHEMBL6469 | 0.85 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1MEN1 | |
| SCHEMBL525493 | 0.85 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1MEN1 | |
| SCHEMBL9977456 | 0.85 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1MEN1 | |
| SCHEMBL5988691 | 0.81 | ALDH1A1 (0.43) | ALDH1A1CTSSCTSKL3MBTL1CTSL | |
| SCHEMBL8234437 | 0.81 | ALDH1A1 (0.43) | ALDH1A1CTSSCTSKL3MBTL1CTSL | |
| SCHEMBL3265211 | 0.81 | ALDH1A1 (0.43) | ALDH1A1CTSSCTSKL3MBTL1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150141326-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141326-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, SARS1 | ALDH1A1 3925/4885CTSS 1067/4885CTSK 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.