Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27321671 | 0.80 | IMPDH2 (0.41) | IMPDH2 | |
| SCHEMBL16411423 | 0.80 | HDAC8 (0.32) | — | |
| SCHEMBL26830920 | 0.68 | — | — | |
| SCHEMBL1671018 | 0.66 | BRD4 (0.36) | — | |
| SCHEMBL20157259 | 0.65 | HDAC8 (0.34) | IMPDH2 | |
| SCHEMBL5153694 | 0.64 | TTR (0.32) | IMPDH2 | |
| SCHEMBL9121897 | 0.64 | IMPDH2 (0.42) | IMPDH2 | |
| SCHEMBL1993105 | 0.64 | IMPDH2 (0.42) | IMPDH2 | |
| SCHEMBL5150772 | 0.64 | IMPDH2 (0.31) | IMPDH2 | |
| SCHEMBL12800964 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |