Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 15/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 11/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16711190 | 0.86 | CSNK1E (0.55) | CSNK1ECSNK1D | |
| SCHEMBL16711450 | 0.80 | CSNK1E (0.52) | CSNK1ECSNK1D | |
| SCHEMBL26645223 | 0.79 | ALDH1A1 (0.48) | CSNK1EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL26645364 | 0.79 | CSNK1E (0.45) | CSNK1ECSNK1DCYP3A4 | |
| SCHEMBL30622855 | 0.79 | CSNK1E (0.42) | CSNK1ECSNK1DUSP30 | |
| SCHEMBL26645056 | 0.79 | CSNK1E (0.42) | CSNK1ECSNK1DUSP30 | |
| SCHEMBL16730688 | 0.79 | CSNK1E (0.63) | CSNK1ECSNK1D | |
| SCHEMBL30623018 | 0.78 | CSNK1E (0.44) | CSNK1ECSNK1D | |
| SCHEMBL30622957 | 0.78 | SUV39H2 (0.44) | CSNK1EALDH1A1 | |
| SCHEMBL26645586 | 0.78 | CSNK1E (0.44) | CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073763-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |