Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 7/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623018 | 1.00 | CSNK1E (0.44) | CSNK1ECFTRCSNK1DSMPD3ABHD6 | |
| SCHEMBL30622957 | 0.89 | SUV39H2 (0.44) | CSNK1ECFTRSMPD3PIK3CDPIK3CA | |
| SCHEMBL26645413 | 0.89 | SUV39H2 (0.44) | CSNK1ECFTRSMPD3PIK3CDPIK3CA | |
| SCHEMBL26645364 | 0.88 | CSNK1E (0.45) | CSNK1ECSNK1DGPR119 | |
| SCHEMBL26645016 | 0.85 | CSNK1E (0.42) | CSNK1ECFTRCSNK1DSMPD3ABHD6 | |
| SCHEMBL30622850 | 0.85 | CSNK1E (0.42) | CSNK1ECFTRCSNK1DSMPD3ABHD6 | |
| SCHEMBL16711450 | 0.85 | CSNK1E (0.52) | CSNK1ECSNK1D | |
| SCHEMBL26645223 | 0.84 | ALDH1A1 (0.48) | CSNK1EGPR119STS | |
| SCHEMBL16711190 | 0.83 | CSNK1E (0.55) | CSNK1ECSNK1D | |
| SCHEMBL26645635 | 0.81 | MAPT (0.46) | CSNK1ECSNK1DGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |