Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TAF1 | P21675 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19929 | 0.84 | — | — | |
| SCHEMBL27952255 | 0.84 | PIK3CB (0.41) | BRD4TAF1BRPF1CREBBPCECR2 | |
| Hydrochloric Acid SCHEMBL6853659 | 0.82 | PIK3CB (0.40) | BRD4TAF1BRPF1CREBBPCECR2 | |
| Iodide SCHEMBL29172953 | 0.82 | PIK3CB (0.40) | BRD4TAF1BRPF1CREBBPCECR2 | |
| Cytosine SCHEMBL1330400 | 0.80 | — | — | |
| Cytosine SCHEMBL4657334 | 0.80 | DYRK1A (0.44) | DYRK1ACRBNADORA2AADORA1 | |
| Cytosine SCHEMBL1330710 | 0.80 | — | — | |
| Cytosine SCHEMBL4059 | 0.80 | — | — | |
| Cytosine SCHEMBL6839378 | 0.79 | NOTUM (0.34) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL28823314 | 0.79 | KDM4E (0.32) | BRD4TAF1BRPF1CREBBPCECR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160177381-A1 | Base-Pair Specific Inter-Strand Locks for Genetic and Epigenetic Detection | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2016-06-23 | — | — | US | claimed |
| WO-2015021055-A1 | BASE-PAIR SPECIFIC INTER-STRAND LOCKS FOR GENETIC AND EPIGENETIC DETECTION | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2015-02-12 | — | — | WO | claimed |
| CN-113661242-A | Compositions comprising modified cyclic polyribonucleotides and uses thereof | 旗舰创业创新第六有限责任公司 | 2021-11-16 | — | — | CN | disclosed |
| US-20160177381-A1 | Base-Pair Specific Inter-Strand Locks for Genetic and Epigenetic Detection | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2016-06-23 | — | — | US | disclosed |
| WO-2015021055-A1 | BASE-PAIR SPECIFIC INTER-STRAND LOCKS FOR GENETIC AND EPIGENETIC DETECTION | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2015-02-12 | — | — | WO | disclosed |
| US-20110091887-A1 | METHOD FOR DETECTION OF METHYLCYTOSINE USING PHOTORESPONSIVE PROBE | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110091887-A1 | METHOD FOR DETECTION OF METHYLCYTOSINE USING PHOTORESPONSIVE PROBE | DNMT1, NT5C3B, MPG | BRD4 1786/4885TAF1 1396/4885BRPF1 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.