SCHEMBL16732008

SCHEMBL16732008

NCCC[C@H](O)[C@H](N)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.50
CPB2 Q96IY4 4/20 0.47
RNPEP Q9H4A4 1/20 0.43
USP2 O75604 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
TRPV1 Q8NER1 1/20 0.39
TRPA1 O75762 1/20 0.39
GABRR1 P24046 3/20 0.38
GABRR3 A8MPY1 1/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
HDAC3 O15379 1/20 0.37
GABBR2 O75899 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
THRB P10828 1/20 0.37
GABRA1 P14867 1/20 0.37
TSHR P16473 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3948254 1.00 GSR (0.50) GSRCPB2RNPEPUSP2SLCO1B1
SCHEMBL2824475 1.00 GSR (0.50) GSRCPB2RNPEPUSP2SLCO1B1
SCHEMBL503258 1.00 GSR (0.50) GSRCPB2RNPEPUSP2SLCO1B1
SCHEMBL358290 1.00 GSR (0.50) GSRCPB2RNPEPUSP2SLCO1B1
Hydrochloric Acid SCHEMBL16760214 0.98 GSR (0.48) GSRCPB2RNPEPUSP2SLCO1B1
Hydrochloric Acid SCHEMBL16760213 0.98 GSR (0.48) GSRCPB2RNPEPUSP2SLCO1B1
Hydrochloric Acid SCHEMBL7107024 0.96 GSR (0.47) GSRCPB2RNPEPUSP2SLCO1B1
Hydrochloric Acid SCHEMBL751303 0.96 GSR (0.47) GSRCPB2RNPEPUSP2SLCO1B1
SCHEMBL16731992 0.86 USP2 (0.46) GSRCPB2RNPEPUSP2SLCO1B1
SCHEMBL2482513 0.86 USP2 (0.46) GSRCPB2RNPEPUSP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4684030-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2026-01-28 EP disclosed
US-20250282818-A1 SYRBACTIN MACROLACTAMS AND UNNATURAL ANALOGS AS PROTEASOME INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA AND CHEMOENZYMATIC SYNTHESIS THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION,INCORPORATED (US) 2025-09-11 US disclosed
WO-2024227957-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2024-11-07 WO disclosed
EP-2889288-B1 METHOD FOR PRODUCING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID DERIVATIVE, AND METHOD FOR PURIFYING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID API CORP (JP) 2018-07-25 EP disclosed
US-9981984-B2 Method for producing cis-5-hydroxy-2-piperidinecarboxylic acid derivative, and method for purifying cis-5-hydroxy-2-piperidinecarboxylic acid API CORPORATION (JP) 2018-05-29 US disclosed
EP-2889378-B1 METHOD FOR PRODUCING HYDROXY-L-LYSINE EMPLOYING AN L-LYSINE HYDROXYLASE AND METHOD FOR PRODUCING HYDROXY-L-PIPECOLIC ACID API CORP (JP) 2018-01-10 EP disclosed
US-9512452-B2 L-lysine hydroxylase and production method for hydroxy-L-lysine and hydroxy-L-pipecolic acid using same API CORPORATION (JP) 2016-12-06 US disclosed
US-20150259715-A1 L-Lysine Hydroxylase and Production Method for Hydroxy-L-Lysine and Hydroxy-L-Pipecolic Acid Using Same API CORPORATION (JP) 2015-09-17 US disclosed
US-20150239906-A1 Method for Producing cis-5-hydroxy-2-piperidinecarboxylic Acid Derivative, and Method for Purifying cis-5-hydroxy-2-piperidinecarboxylic Acid UBE CORPORATION (JP) 2015-08-27 US disclosed
EP-2889378-A1 PRODUCTION METHOD FOR L-LYSINE HYDROXYLASE AND HYDROXY-L-LYSINE USING SAME, AND PRODUCTION METHOD FOR HYDROXY-L-PIPECOLIC ACID API Corporation (JP) 2015-07-01 EP disclosed
EP-2889288-A1 METHOD FOR PRODUCING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID DERIVATIVE, AND METHOD FOR PURIFYING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID API Corporation (JP) 2015-07-01 EP disclosed
WO-2015078889-A1 NEW ENZYMES AND METHOD FOR PREPARING HYDROXYLATED L-LYSINE OR L-ORNITHINE AND ANALOGS THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-06-04 WO disclosed
EP-2876156-A1 New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-05-27 EP disclosed
EP-2876156-A1 New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282818-A1 SYRBACTIN MACROLACTAMS AND UNNATURAL ANALOGS AS PROTEASOME INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA AND CHEMOENZYMATIC SYNTHESIS THEREOF PSMB10, PSMB1, PSMB5 GSR 4408/4885CPB2 954/4885RNPEP 138/4885
US-20150239906-A1 Method for Producing cis-5-hydroxy-2-piperidinecarboxylic Acid Derivative, and Method for Purifying cis-5-hydroxy-2-piperidinecarboxylic Acid HCAR2, HCAR1, C5 GSR 2916/4885CPB2 612/4885RNPEP 1519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.