Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nepodin SCHEMBL30189621 | 1.00 | MEN1 (0.53) | MEN1KMT2AALDH1A1MCL1DNMT1 | |
| SCHEMBL20020387 | 0.83 | MEN1 (0.46) | MEN1KMT2AALDH1A1MCL1DNMT1 | |
| SCHEMBL20020937 | 0.81 | MAPT (0.47) | MAPTGAACYP3A4RECQL | |
| SCHEMBL15782873 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1MCL1DNMT1 | |
| SCHEMBL12800165 | 0.80 | MEN1 (0.49) | MEN1KMT2AALDH1A1MCL1DNMT1 | |
| SCHEMBL29437881 | 0.78 | HSD17B1 (0.36) | MEN1KMT2AALDH1A1THRBMAPT | |
| SCHEMBL12800168 | 0.78 | CYP3A4 (0.52) | MEN1KMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL4742401 | 0.78 | HSD17B1 (0.36) | MEN1KMT2AALDH1A1THRBMAPT | |
| SCHEMBL1672199 | 0.78 | SELL (0.39) | MEN1KMT2ATHRBMAPTGAA | |
| SCHEMBL16433056 | 0.77 | MEN1 (0.46) | MEN1KMT2AALDH1A1MCL1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488152-B1 | COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION | OREAL (FR) | 2018-04-04 | — | — | EP | claimed |
| US-8551189-B2 | Composition comprising at least one 1,8-dihydroxynaphthalene derivative and at least one basifying agent different from aqueous ammonia, process for dyeing keratin fibres using the composition | L'OREAL (FR) | 2013-10-08 | — | — | US | claimed |
| EP-2488152-A2 | COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION | L'Oréal (FR) | 2012-08-22 | — | — | EP | claimed |
| WO-2011045403-A2 | COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION | L'OREAL (FR) | 2011-04-21 | — | — | WO | claimed |
| JP-63088113-A | — | — | None | — | — | JP | disclosed |
| JP-63088111-A | — | — | None | — | — | JP | disclosed |
| CN-118307411-A | Preparation method of 2-acyl naphthol compound | 西北工业大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-118045123-A | Rumex acetosa traditional Chinese medicine composition and application thereof | 三门峡速达绿色能源科技有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-116813676-B | Rumex plant extract and active compound, and preparation method and application thereof | 中国科学院昆明植物研究所 | 2024-03-19 | — | — | CN | disclosed |
| CN-116813676-A | Rumex plant extract and active compound, and preparation method and application thereof | 中国科学院昆明植物研究所 | 2023-09-29 | — | — | CN | disclosed |
| CN-116172925-A | Plant extract for treating dandruff caused by fungi | 赤峰福纳康生物技术有限公司 | 2023-05-30 | — | — | CN | disclosed |
| US-20230148620-A1 | STABILIZED OIL AND METHODS OF MAKING THE SAME | CARGILL, INCORPORATED (US) | 2023-05-18 | — | — | US | disclosed |
| US-6800615-B2 | PARASITICIDES, NEMATOCIDES | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-10-05 | — | — | US | disclosed |
| US-20040152645-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-08-05 | — | — | US | disclosed |
| US-20040116361-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-06-17 | — | — | US | disclosed |
| US-20040106686-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-06-03 | — | — | US | disclosed |
| US-20030229032-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2003-12-11 | — | — | US | disclosed |
| WO-2003089577-A2 | ANTIHELMINTHIC ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | disclosed |
| JP-S6388113-A | HAIR COSMETIC | SHISEIDO CO LTD | 1988-04-19 | — | — | JP | disclosed |
| JP-S6388111-A | MAKE-UP COSMETIC | SHISEIDO CO LTD | 1988-04-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229032-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | MEN1 3190/4885KMT2A 703/4885ALDH1A1 102/4885 |
| US-20040152645-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | MEN1 3190/4885KMT2A 703/4885ALDH1A1 102/4885 |
| US-20040106686-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | MEN1 3190/4885KMT2A 703/4885ALDH1A1 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.