Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437881 | 1.00 | HSD17B1 (0.36) | HSD17B1IDO1CYP3A4THRBMEN1 | |
| Nepodin SCHEMBL1673268 | 0.78 | MEN1 (0.53) | IDO1CYP3A4THRBMEN1HPGD | |
| Nepodin SCHEMBL30189621 | 0.78 | MEN1 (0.53) | IDO1CYP3A4THRBMEN1HPGD | |
| SCHEMBL20020937 | 0.73 | MAPT (0.47) | CYP3A4CA9LMNAMAPTRECQL | |
| SCHEMBL1672199 | 0.72 | SELL (0.39) | IDO1CYP3A4THRBMEN1HPGD | |
| SCHEMBL12800168 | 0.72 | CYP3A4 (0.52) | IDO1CYP3A4MEN1HPGDKMT2A | |
| SCHEMBL9617423 | 0.71 | IDO1 (0.48) | IDO1CYP3A4SMN1; SMN2PTPN11LMNA | |
| SCHEMBL12800166 | 0.69 | MAPT (0.44) | IDO1CYP3A4MEN1HPGDKMT2A | |
| SCHEMBL2046049 | 0.69 | CYP3A4 (0.52) | CYP3A4THRBMEN1HPGDKMT2A | |
| Isotorachrysone SCHEMBL16226209 | 0.68 | CYP3A4 (0.47) | IDO1CYP3A4MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |
| WO-2008100977-A2 | CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS | N.V. ORGANON (NL) | 2008-08-21 | — | — | WO | disclosed |
| US-7132403-B2 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2006-11-07 | — | — | US | disclosed |
| CN-1658757-A | Antihelminthic anthraquinones and method of use thereof | UNIV MICHIGAN (US) | 2005-08-24 | — | — | CN | disclosed |
| US-6903076-B2 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2005-06-07 | — | — | US | disclosed |
| US-6838443-B2 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2005-01-04 | — | — | US | disclosed |
| US-6800615-B2 | PARASITICIDES, NEMATOCIDES | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-10-05 | — | — | US | disclosed |
| US-20040152645-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-08-05 | — | — | US | disclosed |
| US-20040116361-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-06-17 | — | — | US | disclosed |
| US-20040106686-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-06-03 | — | — | US | disclosed |
| US-20030229032-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2003-12-11 | — | — | US | disclosed |
| WO-2003089577-A2 | ANTIHELMINTHIC ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229032-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | HSD17B1 300/4885IDO1 898/4885CYP3A4 627/4885 |
| US-20040152645-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | HSD17B1 300/4885IDO1 898/4885CYP3A4 627/4885 |
| US-20040106686-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | HSD17B1 300/4885IDO1 898/4885CYP3A4 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.