SCHEMBL1673269

SCHEMBL1673269

CCCCCCCCCCCCCC(=O)NC(C)S

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.71
MEN1 O00255 2/20 0.71
KMT2A Q03164 2/20 0.71
MAPK1 P28482 1/20 0.71
DNM1 Q05193 1/20 0.58
HSP90AA1 P07900 1/20 0.55
NOD1 Q9Y239 1/20 0.53
PLA2G2C Q5R387 1/20 0.53
PLA2G10 O15496 2/20 0.53
ASAH2 Q9NR71 1/20 0.51
ALDH1A1 P00352 1/20 0.50
ASAH1 Q13510 1/20 0.50
ACER2 Q5QJU3 1/20 0.50
CPT2 P23786 1/20 0.47
CPT1A P50416 1/20 0.47
CPT1B Q92523 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20734548 1.00 FAAH (0.71) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL9509876 0.98 FAAH (0.68) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL10437118 0.92 FAAH (0.59) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL277126 0.83 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL20143550 0.83 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL4023787 0.83 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
Hexadecanoic Acid Isopropylamide SCHEMBL1457147 0.83 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL2146114 0.83 FAAH (0.77) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL12459875 0.83 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL1456463 0.83 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0912730-B1 CONJUGATES OF SOLUBLE PEPTIDIC COMPOUNDS WITH MEMBRANE-BINDING AGENTS ADPROTECH LTD (GB) 2008-12-31 EP claimed
EP-1097198-A2 SOLUBLE DERIVATIVES OF ANTI-ANGIOGENIC PEPTIDES AdProTech plc (GB) 2001-05-09 EP claimed
WO-2000004052-A2 SOLUBLE DERIVATIVES OF ANTI-ANGIOGENIC PEPTIDES ADPROTECH LIMITED (GB) 2000-01-27 WO claimed
CN-114651014-A IL-15 fusion peptides for the treatment of cancer 前列腺癌研究中心 2022-06-21 CN disclosed
US-20110086808-A1 MODIFIED THERAPEUTIC AGENTS ADPROTECH LIMITED (GB) 2011-04-14 US disclosed
US-7655617-B2 Conjugates of soluble peptidic compounds with membrane-binding agents ADPROTECH LIMITED (GB) 2010-02-02 US disclosed
EP-0912730-B1 CONJUGATES OF SOLUBLE PEPTIDIC COMPOUNDS WITH MEMBRANE-BINDING AGENTS ADPROTECH LTD (GB) 2008-12-31 EP disclosed
EP-0979276-B1 COMPLEMENT RECEPTOR TYPE 1 (CR1)-LIKE SEQUENCES ADPROTECH LTD (GB) 2006-12-13 EP disclosed
US-20060241048-A1 Modified therapeutic agents ADPRO TECH LIMITED (GB) 2006-10-26 US disclosed
EP-1542730-B1 MODIFIED THERAPEUTIC AGENTS ADPROTECH LTD (GB) 2006-06-07 EP disclosed
EP-1542730-A1 MODIFIED THERAPEUTIC AGENTS AdProTech Limited (GB) 2005-06-22 EP disclosed
US-20040266684-A1 Conjugates of soluble peptidic compounds with membrane-binding agents ADPROTECH LIMITED (GB) 2004-12-30 US disclosed
US-6713606-B1 THERAPEUTIC AGENT BOUND VIA LINKER TO A HYDROPHILIC PEPTIDE BINDING ELEMENT OF THE MEMBRANE LOCALIZATION REAGENT TO FORM THE SOLUBLE COMPOUND ADPROTECH LIMITED (GB) 2004-03-30 US disclosed
WO-2004022101-A1 MODIFIED THERAPEUTIC AGENTS ADPROTECH LIMITED (GB) 2004-03-18 WO disclosed
US-20030064431-A1 COMPLEMENT RECEPTOR TYPE 1 (CR1)-LIKE SEQUENCES ADPROTECH LIMITED (GB) 2003-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040266684-A1 Conjugates of soluble peptidic compounds with membrane-binding agents SELPLG, CD2BP2, EPCAM FAAH 3274/4885MEN1 911/4885KMT2A 4177/4885
US-20030064431-A1 COMPLEMENT RECEPTOR TYPE 1 (CR1)-LIKE SEQUENCES LHCGR, FSHR, C3AR1 FAAH 4395/4885MEN1 1212/4885KMT2A 2625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.