Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BMP1 | P13497 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287310 | 0.92 | TAS2R14 (0.56) | TAS2R14BMP1KDM4EALDH1A1PSEN1 | |
| SCHEMBL1287358 | 0.90 | TAS2R14 (0.64) | TAS2R14TSHRPSEN1PSEN2APH1B | |
| SCHEMBL15388045 | 0.89 | TAS2R14 (0.61) | TAS2R14BMP1KDM4EALDH1A1PSEN1 | |
| SCHEMBL15396091 | 0.88 | POLB (0.56) | TAS2R14BMP1KDM4EALDH1A1PSEN1 | |
| SCHEMBL1673452 | 0.87 | TAS2R14 (0.55) | TAS2R14BMP1KDM4EALDH1A1POLB | |
| SCHEMBL15388033 | 0.87 | PSEN1 (0.54) | TAS2R14BMP1KDM4EALDH1A1PSEN1 | |
| SCHEMBL15388094 | 0.87 | PSEN1 (0.59) | TAS2R14BMP1KDM4EALDH1A1PSEN1 | |
| SCHEMBL1674548 | 0.87 | PSEN1 (0.54) | TAS2R14BMP1KDM4EALDH1A1PSEN1 | |
| SCHEMBL15387949 | 0.87 | PSEN1 (0.59) | TAS2R14BMP1KDM4EALDH1A1PSEN1 | |
| SCHEMBL5121744 | 0.86 | TAS2R14 (0.51) | TAS2R14TSHRBMP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |