SCHEMBL1673373

SCHEMBL1673373

O=C(O)c1cc(SS)ccc1[N+](=O)[O-]

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DTYMK P23919 1/20 0.76
CASP6 P55212 1/20 0.46
TSHR P16473 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
POLB P06746 2/20 0.42
TDP1 Q9NUW8 2/20 0.40
TTR P02766 1/20 0.40
PPOX P50336 1/20 0.40
BCL2L1 Q07817 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
LMNA P02545 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL504562 0.86 DTYMK (0.81) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL26775 0.86 DTYMK (1.00) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL29353295 0.86 DTYMK (1.00) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL143541 0.86 DTYMK (1.00) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL29388000 0.85 DTYMK (0.97) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL2470206 0.85 DTYMK (0.78) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL8577281 0.85 DTYMK (0.97) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL4820050 0.83 DTYMK (0.76) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL19292717 0.81 SIRT6 (0.52) DTYMKMEN1KMT2ATDP1ALDH1A1
SCHEMBL13715527 0.81 DTYMK (0.82) DTYMKCASP6TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080108557-A1 Modified Proteins NOVO NORDISK HEALTHCARE A/G (CH) 2008-05-08 US claimed
EP-1797192-A1 MODIFIED PROTEINS Novo Nordisk Health Care AG (CH) 2007-06-20 EP claimed
US-20070029529-A1 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor KOMATSU AKIHIKO 2007-02-08 US claimed
WO-2006035057-A1 MODIFIED PROTEINS NOVO NORDISK HEALTH CARE AG (DK) 2006-04-06 WO claimed
US-20040245105-A1 Electrolyte solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2004-12-09 US claimed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 EP claimed
CN-1126436-A Vitamin B12 mediated oral delivery systems for GCSF and EPO BIOTECH AUSTRALIA PTY LTD (AU) 1996-07-10 CN claimed
EP-3621989-B1 METHOD OF CONTROLLING THE FORMATION OF PINK COLOR DURING ANTIBODY MANUFACTURING BRISTOL MYERS SQUIBB CO (US) 2023-06-28 EP disclosed
US-20230103511-A1 METHOD OF CONTROLLING THE PINK COLOR GENERATED DURING ANTIBODY MANUFACTURING BRISTOL-MYERS SQUIBB COMPANY (US) 2023-04-06 US disclosed
EP-3621989-A1 METHOD OF CONTROLLING THE FORMATION OF PINK COLOR DURING ANTIBODY MANUFACTURING Bristol-Myers Squibb Company (US) 2020-03-18 EP disclosed
CN-110831964-A Method of controlling pink color formation during antibody manufacture 百时美施贵宝公司 2020-02-21 CN disclosed
WO-2018208743-A9 METHOD OF CONTROLLING THE FORMATION OF PINK COLOR DURING ANTIBODY MANUFACTURING BRISTOL-MYERS SQUIBB COMPANY (US) 2019-12-05 WO disclosed
WO-2018208743-A1 METHOD OF CONTROLLING THE FORMATION OF PINK COLOR DURING ANTIBODY MANUFACTURING BRISTOL-MYERS SQUIBB COMPANY (US) 2018-11-15 WO disclosed
US-5041658-A Indicator generates a variety of hues depending on the analyte concentration MILES INC. (US) 1991-08-20 US disclosed
US-5026897-A Chemically mask cholinesterase enzymes; antispasmotic agents THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1991-06-25 US disclosed
US-4975367-A Catalytic test composition intended to produce a range of colors MILES INC. (US) 1990-12-04 US disclosed
US-4973734-A ANTIDIOTE FOR ORGANOPPHOSPHATE POISONING THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1990-11-27 US disclosed
US-4898813-A Catalytic test composition intended to produce a range of colors MILES INC. 1990-02-06 US disclosed
EP-0240849-A2 Controlled hue test device MILES INC. (US) 1987-10-14 EP disclosed
EP-0239926-A2 Rainbow test device MILES INC. (US) 1987-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080108557-A1 Modified Proteins PTMS, DNPEP, STT3A DTYMK 266/4885CASP6 4095/4885TSHR 3069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.