SCHEMBL16735433

SCHEMBL16735433

O=C1C(c2ccccc2)=C(c2ccccc2)C(c2ccccc2)=C1c1ccccc1-c1ccccc1C1=C(c2ccccc2)C(c2ccccc2)=C(c2ccccc2)C1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 4/20 0.55
FGFR2 P21802 4/20 0.55
FGFR4 P22455 4/20 0.55
FGFR3 P22607 4/20 0.55
CDC25B P30305 3/20 0.53
CDC25A P30304 1/20 0.53
P2RX7 Q99572 1/20 0.52
SRC P12931 2/20 0.52
CRHBP P24387 1/20 0.52
CRHR2 Q13324 1/20 0.52
MAPT P10636 4/20 0.50
NPSR1 Q6W5P4 4/20 0.50
LMNA P02545 4/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
HTT P42858 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
APAF1 O14727 2/20 0.50
NPC1 O15118 2/20 0.50
THRB P10828 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16735427 1.00 FGFR1 (0.55) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL27649289 0.95 FGFR1 (0.52) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL22143430 0.95 FGFR1 (0.55) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL516326 0.89 PDE4B (0.54) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL20160837 0.87 PDE4B (0.52) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL13170491 0.87 PDE4B (0.52) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL4250744 0.87 PDE4B (0.52) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL13170578 0.87 PDE4B (0.52) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL740371 0.85 FGFR1 (0.61) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL5497788 0.84 MAPT (0.65) FGFR1FGFR2FGFR4FGFR3CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3078698-B1 POLYARYLENE POLYMERS ROHM & HAAS ELECT MAT (US) 2019-11-20 EP disclosed
US-9752051-B2 Polyarylene polymers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2017-09-05 US disclosed
EP-3078698-A1 POLYARYLENE POLYMERS Rohm and Haas Electronic Materials LLC (US) 2016-10-12 EP disclosed
US-20160289493-A1 POLYARYLENE POLYMERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-10-06 US disclosed
US-20150147463-A1 DIELECTRIC MATERIALS ROHM AND HAAS ELECRONIC MATERIALS LLC 2015-05-28 US disclosed
EP-2876123-A1 Dielectric materials Rohm and Haas Electronic Materials LLC (US) 2015-05-27 EP disclosed