SCHEMBL740371

SCHEMBL740371

O=C1C(c2ccccc2)=C(c2ccccc2)c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 4/20 0.61
FGFR2 P21802 4/20 0.61
FGFR4 P22455 4/20 0.61
FGFR3 P22607 4/20 0.61
MAPT P10636 4/20 0.61
NPSR1 Q6W5P4 3/20 0.61
ALDH1A1 P00352 2/20 0.61
HTT P42858 2/20 0.61
MITF O75030 1/20 0.61
CDC25B P30305 3/20 0.59
CDC25A P30304 1/20 0.59
ESR1 P03372 2/20 0.58
ESR2 Q92731 2/20 0.58
P2RX7 Q99572 1/20 0.57
LMNA P02545 3/20 0.57
HSP90AA1 P07900 3/20 0.57
HSP90AB1 P08238 3/20 0.57
SRC P12931 2/20 0.57
CRHBP P24387 1/20 0.57
CRHR2 Q13324 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5497788 0.95 MAPT (0.65) FGFR1FGFR2FGFR4FGFR3MAPT
SCHEMBL16735427 0.85 FGFR1 (0.55) FGFR1FGFR2FGFR4FGFR3MAPT
SCHEMBL22143430 0.85 FGFR1 (0.55) FGFR1FGFR2FGFR4FGFR3MAPT
SCHEMBL16735433 0.85 FGFR1 (0.55) FGFR1FGFR2FGFR4FGFR3MAPT
SCHEMBL3252409 0.83 PTGS2 (0.68) ALDH1A1
SCHEMBL7878297 0.83 PTGS2 (0.62) FGFR1FGFR2FGFR4FGFR3MAPT
SCHEMBL10502062 0.82 MAPT (0.53) FGFR1FGFR2FGFR4FGFR3MAPT
SCHEMBL27649289 0.81 FGFR1 (0.52) FGFR1FGFR2FGFR4FGFR3MAPT
SCHEMBL19879495 0.81 ALDH1A1 (0.50) FGFR1FGFR2FGFR4FGFR3MAPT
SCHEMBL7645971 0.80 PSIP1 (0.53) FGFR1FGFR2FGFR4FGFR3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10092786-B2 Fire extinguishing composition comprising aldoketones compound XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) 2018-10-09 US claimed
US-20160332016-A1 Fire Extinguishing Composition Comprising Aldoketones Compound NANO FIRE, LLC 2016-11-17 US claimed
EP-1258349-B1 Method for the preparation of a negative working printing plate AGFA GEVAERT (BE) 2005-04-20 EP claimed
EP-1263590-B1 THERMALLY IMAGEABLE ELEMENT AND LITHOGRAPHIC PRINTING PLATE KODAK POLYCHROME GRAPHICS CO (US) 2005-03-16 EP claimed
US-6777164-B2 A POLYMER WITH HYDROXY GROUPS ABLE TO REACT WITH A COLORANT COMPOUND, COATED ON ALUMINUM SUBSTRATE WHICH IS ANODIZED, AND COATING DOES NOT CONTAIN A FREE COLORANT DYE KODAK POLYCHROME GRAPHICS LLC 2004-08-17 US claimed
US-6739260-B2 Method for the preparation of a negative working printing plate AGFA-GEVAERT (BE) 2004-05-25 US claimed
EP-1400369-A2 Pattern formation Kodak Polychrome Graphics Company Ltd. (US) 2004-03-24 EP claimed
EP-1398170-A2 Pattern formation Kodak Polychrome Graphics Company Ltd. (US) 2004-03-17 EP claimed
US-6558869-B1 Heat sensitive composition, the solubility of which in an aqueous alkaline developer is arranged to increase in heated areas, and a developer resistance means for increasing the resistance of non-heated areas KODAK POLYCHROME GRAPHICS LLC 2003-05-06 US claimed
US-20030005838-A1 Method for the preparation of a negative working printing plate AGFA GRAPHICS NV (BE) 2003-01-09 US claimed
EP-0914392-A1 LUMINESCING INKS AND USE OF SUCH INKS IN CODING AND OTHER MARKING OPERATIONS THE POST OFFICE (GB) 1999-05-12 EP claimed
WO-1999021725-A1 PATTERN FORMATION KODAK POLYCHROME GRAPHICS COMPANY LTD (US) 1999-05-06 WO claimed
WO-1999021715-A1 MANUFACTURE OF LITHOGRAPHIC PRINTING FORMS KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 1999-05-06 WO claimed
WO-1998054621-A1 METHODS OF IMAGING AND PRINTING WITH A POSITIVE-WORKING INFRARED RADIATION SENSITIVE PRINTING PLATE KODAK POLYCHROME GRAPHICS, L.L.C. (US) 1998-12-03 WO claimed
WO-1998042507-A1 POSITIVE-WORKING INFRARED RADIATION SENSITIVE COMPOSITION AND PRINTING PLATE AND IMAGING METHOD KODAK POLYCHROME GRAPHICS, L.L.C. (US) 1998-10-01 WO claimed
EP-0825927-A1 HEAT-SENSITIVE COMPOSITION AND METHOD OF MAKING A LITHOGRAPHIC PRINTING FORM WITH IT HORSELL GRAPHIC INDUSTRIES LIMITED (GB) 1998-03-04 EP claimed
WO-1998003596-A1 LUMINESCING INKS AND USE OF SUCH INKS IN CODING AND OTHER MARKING OPERATIONS THE POST OFFICE (GB) 1998-01-29 WO claimed
WO-1997039894-A1 HEAT-SENSITIVE COMPOSITION AND METHOD OF MAKING A LITHOGRAPHIC PRINTING FORM WITH IT HORSELL GRAPHIC INDUSTRIES LIMITED (GB) 1997-10-30 WO claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
US-4356255-A Photosensitive members and a process for forming patterns using the same FUJI PHOTO FILM CO., LTD. (JP) 1982-10-26 US claimed