SCHEMBL4250744

SCHEMBL4250744

O=C1C(c2ccccc2)=C(c2ccccc2)C(c2ccc(C3=C(c4ccccc4)C(=O)C(c4ccccc4)=C3c3ccccc3)cc2)=C1c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.52
ESR1 P03372 4/20 0.48
ESR2 Q92731 4/20 0.48
MAPT P10636 4/20 0.48
HTT P42858 4/20 0.48
LMNA P02545 3/20 0.48
NPSR1 Q6W5P4 3/20 0.48
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
APAF1 O14727 2/20 0.48
NPC1 O15118 2/20 0.48
THRB P10828 2/20 0.48
RAB9A P51151 2/20 0.48
GALK1 P51570 2/20 0.48
BLM P54132 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
XBP1 P17861 1/20 0.48
PTBP1 P26599 1/20 0.48
SMAD3 P84022 1/20 0.48
ATM Q13315 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13170491 1.00 PDE4B (0.52) PDE4BESR1ESR2MAPTHTT
SCHEMBL20160837 1.00 PDE4B (0.52) PDE4BESR1ESR2MAPTHTT
SCHEMBL13170578 1.00 PDE4B (0.52) PDE4BESR1ESR2MAPTHTT
SCHEMBL20160807 0.97 LMNA (0.52) PDE4BESR1ESR2MAPTHTT
SCHEMBL516326 0.97 PDE4B (0.54) PDE4BESR1ESR2MAPTHTT
Ethyne SCHEMBL28292549 0.92 PDE4B (0.50) PDE4BESR1ESR2MAPTHTT
SCHEMBL7192214 0.89 PDE4B (0.48) PDE4BESR1ESR2MAPTHTT
SCHEMBL8693759 0.88 PDE4B (0.52) PDE4BMAPTHTTLMNANPSR1
SCHEMBL25446505 0.88 PDE4B (0.43) PDE4BESR1ESR2MAPTHTT
SCHEMBL7519728 0.88 PTGS1 (0.56) PDE4BESR1ESR2MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025102165-A1 METHOD OF MAKING SULFONATED POLYPHENYLENES IONOMR INNOVATIONS INC. (CA) 2025-05-22 WO disclosed
US-20250163212-A1 METHOD OF MAKING SULFONATED POLYPHENYLENES IONOMR INNOVATIONS INC. (CA) 2025-05-22 US disclosed
US-20240213508-A1 FLUORINE-CONTAINING COMPOUND HAVING SULFONIC ACID GROUP AND POLYMER ELECTROLYTE FUEL CELL NISSAN CHEMICAL CORPORATION (JP) 2024-06-27 US disclosed
US-20240213508-A1 FLUORINE-CONTAINING COMPOUND HAVING SULFONIC ACID GROUP AND POLYMER ELECTROLYTE FUEL CELL NISSAN CHEMICAL CORPORATION (JP) 2024-06-27 US disclosed
EP-3538623-B1 COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP MERCK PATENT GMBH (DE) 2023-12-20 EP disclosed
US-20230354701-A1 COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP MERCK PATENT GMBH (DE) 2023-11-02 US disclosed
US-20230354701-A1 COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP MERCK PATENT GMBH (DE) 2023-11-02 US disclosed
EP-4271163-A2 COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP Merck Patent GmbH (DE) 2023-11-01 EP disclosed
US-11802187-B2 Polyphenylenes, methods, and uses thereof SIMON FRASER UNIVERSITY (CA) 2023-10-31 US disclosed
US-11802187-B2 Polyphenylenes, methods, and uses thereof SIMON FRASER UNIVERSITY (CA) 2023-10-31 US disclosed
US-20090264544-A1 Polyarylene polymers and ion conducting functionalized polyarylene polymers resulting from pairing bis-diene arylenes and bis-dienophile arylenes via a diels-alder reaction ENERGY MATERIALS CORPORATION 2009-10-22 US disclosed
US-20090264544-A1 Polyarylene polymers and ion conducting functionalized polyarylene polymers resulting from pairing bis-diene arylenes and bis-dienophile arylenes via a diels-alder reaction ENERGY MATERIALS CORPORATION 2009-10-22 US disclosed
US-20090264544-A1 Polyarylene polymers and ion conducting functionalized polyarylene polymers resulting from pairing bis-diene arylenes and bis-dienophile arylenes via a diels-alder reaction ENERGY MATERIALS CORPORATION 2009-10-22 US disclosed
US-20090240062-A1 COMPOUND DERIVED FROM CYCLOPENTADIENONE, PREPARATION METHOD THEREOF AND EL ELEMENT USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-09-24 US disclosed
US-20090240062-A1 COMPOUND DERIVED FROM CYCLOPENTADIENONE, PREPARATION METHOD THEREOF AND EL ELEMENT USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-09-24 US disclosed
US-6800381-B2 FOR USE AS ELECTRO-LUMINESCENCE MATERIAL; LIGHT-EMITTING MATERIAL KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2004-10-05 US disclosed
US-20030099838-A1 Fluorene compound, polymers thereof having a polyphenylene group, and EL element comprising the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 2003-05-29 US disclosed
EP-0889920-B1 POLYPHENYLENE OLIGOMERS AND POLYMERS DOW CHEMICAL CO (US) 2002-02-13 EP disclosed
US-6288188-B1 ACETYLENIC POLYMERS; INTEGRATED CIRCUITS, DIELECTRICS, MICROELECTRONICS THE DOW CHEMICAL COMPANY 2001-09-11 US disclosed
US-5965679-A BASED A BISCYCLOPENTADIENONE AND AN AROMATIC DIACETYLENE; CURING; LOW DIELECTRIC; INTEGRATED CIRCUITS; MICROELECTRONICS; PRINTED CIRCUITS THE DOW CHEMICAL COMPANY (US) 1999-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240062-A1 COMPOUND DERIVED FROM CYCLOPENTADIENONE, PREPARATION METHOD THEREOF AND EL ELEMENT USING THE SAME ELP1, CYP51A1, ELOVL1 PDE4B 1946/4885ESR1 272/4885ESR2 125/4885
US-11802187-B2 Polyphenylenes, methods, and uses thereof PICALM, PARN, PHOSPHO1 PDE4B 4017/4885ESR1 1515/4885ESR2 2370/4885
US-20230354701-A1 COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP NQO1, ICMT, NUDT1 PDE4B 2885/4885ESR1 46/4885ESR2 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.