Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.70 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | FERMT2 | Q96AC1 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT5B | Q4FZB7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596040 | 0.83 | NR4A2 (1.00) | NR4A2SOS2CYP1A2FERMT2MAPT | |
| SCHEMBL21101482 | 0.75 | NR4A2 (1.00) | NR4A2SOS2CYP1A2FERMT2MAPT | |
| SCHEMBL2708504 | 0.74 | NR4A2 (0.59) | NR4A2SOS2CYP1A2FERMT2MAPT | |
| SCHEMBL5765299 | 0.73 | NR4A2 (0.58) | NR4A2SOS2CYP1A2FERMT2MAPT | |
| SCHEMBL10424586 | 0.71 | NR4A2 (0.56) | NR4A2SOS2CYP1A2FERMT2MAPT | |
| SCHEMBL20494859 | 0.71 | NR4A2 (0.56) | NR4A2SOS2CYP1A2FERMT2MAPT | |
| SCHEMBL29392254 | 0.71 | NR4A2 (0.56) | NR4A2SOS2CYP1A2FERMT2MAPT | |
| SCHEMBL16735797 | 0.71 | NR4A2 (0.51) | NR4A2SOS2CYP1A2FERMT2MAPT | |
| SCHEMBL29396540 | 0.71 | NR4A2 (0.66) | NR4A2SOS2CYP1A2FERMT2MAPT | |
| SCHEMBL317202 | 0.71 | NR4A2 (0.66) | NR4A2SOS2CYP1A2FERMT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268618-B1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | NOVARTIS AG (CH) | 2015-05-27 | — | — | EP | disclosed |