Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15607119 | 0.85 | CYP2D6 (0.60) | MAPTRAB9AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15618832 | 0.84 | RAB9A (0.77) | KDM4EMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL6705914 | 0.83 | MCHR1 (0.72) | KDM4ERAB9AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3876341 | 0.81 | KDM4E (0.76) | KDM4EMAPTRAB9AKMT2APOLB | |
| SCHEMBL5863404 | 0.81 | LMNA (0.74) | KDM4EMAPTALDH1A1KMT2APOLB | |
| SCHEMBL16562233 | 0.80 | HPGD (0.59) | KDM4EMAPTRAB9AALDH1A1HPGD | |
| SCHEMBL9313096 | 0.79 | MAPT (0.71) | KDM4EMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL6570625 | 0.79 | RAB9A (0.70) | KDM4EMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL3871649 | 0.79 | KDM4E (0.55) | KDM4EMAPTRAB9AALDH1A1POLB | |
| SCHEMBL3868681 | 0.79 | KDM4E (0.55) | KDM4EMAPTRAB9AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170027890-A1 | SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2017-02-02 | — | — | US | disclosed |
| US-9456998-B2 | Selective inhibitors of undifferentiated cells | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2016-10-04 | — | — | US | disclosed |
| US-20150148359-A1 | SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170027890-A1 | SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS | MCL1, MKI67, SCD | KDM4E 2190/4885MAPT 4089/4885RAB9A 3123/4885 |
| US-20150148359-A1 | SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS | MCL1, MKI67, SCD | KDM4E 2190/4885MAPT 4089/4885RAB9A 3123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.