SCHEMBL167388

SCHEMBL167388

O=C(O)C[C@H](NCC=C[SiH3])C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
TDP1 Q9NUW8 1/20 0.33
MME P08473 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
FNTA P49354 2/20 0.32
FNTB P49356 2/20 0.32
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
EPHX2 P34913 2/20 0.31
HDAC2 Q92769 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11499007 0.82 CA2 (0.38) CA2CA4TDP1MMESMN1; SMN2
SCHEMBL9840749 0.81 CA2 (0.37) CA2CA4TDP1MMESMN1; SMN2
SCHEMBL3079588 0.77 CA2 (0.45) CA2CA4TDP1MMEFNTA
SCHEMBL176161 0.76 CA2 (0.39) CA2CA4TDP1MMESMN1; SMN2
SCHEMBL176159 0.76 CA2 (0.39) CA2CA4TDP1MMESMN1; SMN2
SCHEMBL28882688 0.76 CA2 (0.39) CA2CA4TDP1MMESMN1; SMN2
SCHEMBL28882690 0.76 CA2 (0.39) CA2CA4TDP1MMESMN1; SMN2
SCHEMBL8994505 0.74 CA2 (0.38) CA2CA4TDP1MMESMN1; SMN2
SCHEMBL15637714 0.72 CA2 (0.45) CA2CA4TDP1MMESMN1; SMN2
SCHEMBL5825896 0.72 CA2 (0.45) CA2CA4TDP1MMESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3024865-B1 MOISTURE CURABLE COMPOSITIONS WITH ENHANCED ELONGATION AND TEAR PROPERTIES MOMENTIVE PERFORMANCE MAT INC (US) 2019-10-09 EP disclosed
EP-2691464-B1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE MOMENTIVE PERFORMANCE MAT INC (US) 2019-01-09 EP disclosed
US-9932437-B2 Moisture curable silylated polymer compositions containing reactive modifiers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-04-03 US disclosed
US-9714315-B2 Moisture curable silylated polymer compositions containing reactive modifiers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-07-25 US disclosed
EP-2424949-B1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS MOMENTIVE PERFORMANCE MAT INC (US) 2017-03-01 EP disclosed
US-9156981-B2 Moisture curable compositions with enhanced elongation and tear strength properties MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-10-13 US disclosed
US-20150031806-A1 MOISTURE CURABLE COMPOSITIONS WITH ENHANCED ELONGATION AND TEAR STRENTGH PROPERTIES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-01-29 US disclosed
US-20140323650-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS MOMENTIVE PERFORMANCE MATERIALS INC. 2014-10-30 US disclosed
US-8859674-B2 Moisture curable silylated polymer compositions with improved adhesion to concrete MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-10-14 US disclosed
US-8809479-B2 Moisture curable silylated polymer compositions containing reactive modifiers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-08-19 US disclosed
US-20130245194-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-09-19 US disclosed
US-20120251832-A1 Moisture Curable Silylated Polymer Compositions With Improved Adhesion to Concrete MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-10-04 US disclosed
EP-2424949-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS Momentive Performance Materials Inc. (US) 2012-03-07 EP disclosed
US-20100317796-A1 Moisture Curable Silylated Polymer Compositions Containing Reactive Modifiers MOMENTIVE PERFORMANCE MATERIALS INC. 2010-12-16 US disclosed
WO-2010126937-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-04 WO disclosed