Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499007 | 0.82 | CA2 (0.38) | CA2CA4FNTAFNTBTDP1 | |
| SCHEMBL15313369 | 0.81 | FOLH1 (0.48) | FNTAFNTBGAA | |
| SCHEMBL167388 | 0.81 | CA2 (0.37) | CA2CA4FNTAFNTBTDP1 | |
| SCHEMBL3079588 | 0.77 | CA2 (0.45) | CA2CA4FNTAFNTBTDP1 | |
| SCHEMBL28882688 | 0.76 | CA2 (0.39) | CA2CA4FNTAFNTBTDP1 | |
| SCHEMBL176161 | 0.76 | CA2 (0.39) | CA2CA4FNTAFNTBTDP1 | |
| SCHEMBL28882690 | 0.76 | CA2 (0.39) | CA2CA4FNTAFNTBTDP1 | |
| SCHEMBL176159 | 0.76 | CA2 (0.39) | CA2CA4FNTAFNTBTDP1 | |
| SCHEMBL8994505 | 0.74 | CA2 (0.38) | CA2CA4FNTAFNTBTDP1 | |
| SCHEMBL5825896 | 0.72 | CA2 (0.45) | CA2CA4TDP1MMESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001254-A | Novel method for the preparation of quinoline-2,3-dicarboxylic | AMERICAN CYANAMID COMPANY | 1991-03-19 | — | — | US | disclosed |
| EP-0262305-B1 | METHOD FOR THE PREPARATION OF ANILINOFUMARATE AND QUINOLINE-2,3-DICARBOXYLIC ACID | AMERICAN CYANAMID COMPANY (US) | 1990-10-31 | — | — | EP | disclosed |
| US-4766218-A | CYCLIZATION OF DICHLOROSUCCINATE WITH AMINE | AMERICAN CYANAMID COMPANY (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0262305-A1 | Method for the preparation of anilinofumarate and quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID COMPANY (US) | 1988-04-06 | — | — | EP | disclosed |