SCHEMBL16740539

SCHEMBL16740539

C=CC(=O)Oc1ccco1.[NaH]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.45
MMP9 P14780 1/20 0.45
MMP12 P39900 1/20 0.45
THRB P10828 5/20 0.41
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
TYMS P04818 1/20 0.36
KMT2A Q03164 6/20 0.36
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 1/20 0.36
THRA P10827 1/20 0.35
HCAR2 Q8TDS4 1/20 0.34
POLB P06746 5/20 0.34
SRC P12931 1/20 0.34
MEN1 O00255 3/20 0.33
PTPN1 P18031 2/20 0.33
BLM P54132 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NPC1 O15118 1/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1067780 0.98 MMP1 (0.46) MMP1MMP9MMP12THRBCES2
Hydrochloric Acid SCHEMBL27503577 0.96 MMP1 (0.45) MMP1MMP9MMP12THRBCES2
Tetrahydrofuran SCHEMBL10688448 0.87 MMP1 (0.39) MMP1MMP9MMP12THRBCES2
SCHEMBL29468117 0.82 MMP1 (0.49) MMP1MMP9MMP12CES2CES1
Methacrylic Acid SCHEMBL11881403 0.82 THRB (0.38) MMP1MMP9MMP12THRBKMT2A
SCHEMBL27622422 0.81 MMP1 (0.47) MMP1MMP9MMP12THRBCES2
Water SCHEMBL27331748 0.79 MMP1 (0.46) MMP1MMP9MMP12THRBCES2
SCHEMBL11881396 0.78 TSHR (0.40) MMP1MMP9MMP12THRBKMT2A
SCHEMBL6990198 0.76
SCHEMBL7024452 0.76 MMP1 (0.53) MMP1MMP9MMP12THRBCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3071602-B1 NANOFIBERS CONTAINING PHOTOCURABLE ESTER DERIVATIVE OF HYALURONIC ACID OR ITS SALT, PHOTOCURED NANOFIBERS, METHOD OF SYNTHESIS THEREOF, PREPARATION CONTAINING PHOTOCURED NANOFIBERS AND USE THEREOF CONTIPRO AS (CZ) 2017-08-23 EP disclosed
US-20160312385-A1 Nanofibers Containing Photocurable Ester Derivative of Hyaluronic Acid or Its Salt, Photocured Nanofibers, Method of Synthesis Thereof, Preparation Containing Photocured Nanofibers and Use Thereof CONTIPRO A.S. (CZ) 2016-10-27 US disclosed
EP-3071602-A1 NANOFIBERS CONTAINING PHOTOCURABLE ESTER DERIVATIVE OF HYALURONIC ACID OR ITS SALT, PHOTOCURED NANOFIBERS, METHOD OF SYNTHESIS THEREOF, PREPARATION CONTAINING PHOTOCURED NANOFIBERS AND USE THEREOF Contipro Biotech s.r.o. (CZ) 2016-09-28 EP disclosed
WO-2015074632-A1 NANOFIBERS CONTAINING PHOTOCURABLE ESTER DERIVATIVE OF HYALURONIC ACID OR ITS SALT, PHOTOCURED NANOFIBERS, METHOD OF SYNTHESIS THEREOF, PREPARATION CONTAINING PHOTOCURED NANOFIBERS AND USE THEREOF CONTIPRO BIOTECH S R.O. (CZ) 2015-05-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160312385-A1 Nanofibers Containing Photocurable Ester Derivative of Hyaluronic Acid or Its Salt, Photocured Nanofibers, Method of Synthesis Thereof, Preparation Containing Photocured Nanofibers and Use Thereof CD44, SHH, MMP1 MMP1 3/4885MMP9 85/4885MMP12 1154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.