⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28750266 | 0.98 | ALDH1A1 (0.53) | — | |
| SCHEMBL10848329 | 0.84 | F2 (0.47) | — | |
| SCHEMBL8711244 | 0.82 | ALDH1A1 (0.51) | — | |
| SCHEMBL7140275 | 0.82 | ALDH1A1 (0.54) | — | |
| SCHEMBL27623978 | 0.80 | ALDH1A1 (0.57) | — | |
| SCHEMBL3742201 | 0.79 | ALDH1A1 (0.52) | — | |
| SCHEMBL216529 | 0.78 | — | — | |
| SCHEMBL301866 | 0.76 | — | — | |
| SCHEMBL7152839 | 0.76 | — | — | |
| SCHEMBL220742 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1400973-A | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2003-03-05 | — | — | CN | claimed |
| US-20250282785-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2025-09-11 | — | — | US | disclosed |
| EP-4522608-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN Pharmaceutica NV (BE) | 2025-03-19 | — | — | EP | disclosed |
| CN-115586273-B | Compound non-targeting identification method based on bromine isotope labeling | 遵义医科大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-119546602-A | Pyrrolidone derivatives as inhibitors of nfkb-induced kinase | 詹森药业有限公司 | 2025-02-28 | — | — | CN | disclosed |
| US-20240131007-A1 | METHODS AND COMPOSITIONS FOR PICORNAVIRUS ANTI-VIRAL AGENTS | UNIVERSITY OF CONNECTICUT | 2024-04-25 | — | — | US | disclosed |
| WO-2023217906-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-16 | — | — | WO | disclosed |
| CN-116041975-B | Graphene nano-sheet/block copolymer composite modified asphalt, and preparation method and application thereof | 山东交通学院 | 2023-10-03 | — | — | CN | disclosed |
| CN-116041975-A | Graphene nano-sheet/block copolymer composite modified asphalt, and preparation method and application thereof | 山东交通学院 | 2023-05-02 | — | — | CN | disclosed |
| CN-116003307-A | Aryl sulfonyl pyrrole derivative substituted by aromatic formamide and application thereof | 美迪西普亚医药科技(上海)有限公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |
| WO-1995028400-A1 | NOVEL BENZOFUSED 5-MEMBERED HETEROCYCLIC RINGS FOR THE TREATMENT OF MIGRAINE | GLAXO GROUP LIMITED (GB) | 1995-10-26 | — | — | WO | disclosed |
| CN-1023479-C | Process for preparing monoamide derivatives of ethylenediamine | HOFFMANN LA ROCHE (CH) | 1994-01-12 | — | — | CN | disclosed |
| US-4695634-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1987-09-22 | — | — | US | disclosed |
| CN-85107182-A | Process for preparing monoamide derivatives of ethylenediamine | — | 1987-04-08 | — | — | CN | disclosed |
| US-4622406-A | CHEMICAL INTERMEDIATES, TRIMETHYLSILOXY COMPOUNDS | PFIZER INC. (US) | 1986-11-11 | — | — | US | disclosed |
| US-4562267-A | Intermediates of hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1985-12-31 | — | — | US | disclosed |
| US-4423233-A | ALPHA-HYDROXY CARBOXIMIDATE INTERMEDIATES | PFIZER INC. (US) | 1983-12-27 | — | — | US | disclosed |
| US-4381308-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-04-26 | — | — | US | disclosed |
| US-4332952-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1982-06-01 | — | — | US | disclosed |