SCHEMBL16742973

SCHEMBL16742973

O=[N+]([O-])c1cncnc1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
CYP1A2 P05177 3/20 0.38
CYP3A4 P08684 3/20 0.38
CYP2C19 P33261 2/20 0.38
AAK1 Q2M2I8 1/20 0.35
ERN1 O75460 1/20 0.35
ALDH1A1 P00352 7/20 0.34
MAPT P10636 5/20 0.34
HTT P42858 3/20 0.33
MAPK1 P28482 3/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 2/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33
NPC1 O15118 1/20 0.32
S1PR4 O95977 1/20 0.32
HSP90AA1 P07900 1/20 0.32
S1PR1 P21453 1/20 0.32
AGTR1 P30556 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1437304 0.75 MEN1 (0.53) MEN1KMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL11746342 0.75 MEN1 (0.38) MEN1KMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL997756 0.75 PIN1 (0.41) MEN1KMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL4070781 0.75 TDP1 (0.39) MEN1KMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL1699168 0.75 ERN1 (0.41) MEN1KMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL2602424 0.75 ALDH1A1 (0.39) MEN1KMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL4663306 0.75 MEN1 (0.35) MEN1KMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL4874074 0.75 ALDH1A1 (0.41) MEN1KMT2ACYP1A2CYP3A4CYP2C19
Hydrochloric Acid SCHEMBL31546288 0.73 MEN1 (0.51) MEN1KMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL15543211 0.73 MAPT (0.37) KMT2AALDH1A1MAPTHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015076600-A1 NOVEL LIGHT EMISSION COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 동진쎄미켐 2015-05-28 WO disclosed