Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015603 | 0.83 | NPC1 (0.49) | MRGPRX4 | |
| SCHEMBL12128991 | 0.78 | MRGPRX4 (0.55) | MRGPRX4 | |
| SCHEMBL3724878 | 0.78 | NPC1 (0.46) | — | |
| SCHEMBL10349092 | 0.78 | MRGPRX4 (0.55) | MRGPRX4 | |
| SCHEMBL22469883 | 0.78 | MRGPRX4 (0.69) | MRGPRX4 | |
| SCHEMBL3736949 | 0.78 | TDP1 (0.56) | MRGPRX4 | |
| SCHEMBL11008861 | 0.77 | MRGPRX4 (0.51) | MRGPRX4 | |
| Ammonia Solution, Strong SCHEMBL16195080 | 0.77 | MRGPRX4 (0.54) | MRGPRX4 | |
| SCHEMBL4011359 | 0.76 | CYP2C19 (0.73) | MRGPRX4 | |
| SCHEMBL11757129 | 0.76 | MASP2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071578-A1 | TRICYCLIC PIPERIDINE COMPOUNDS | Actelion Pharmaceuticals Ltd (CH) | 2016-09-28 | — | — | EP | claimed |
| WO-2015075023-A1 | TRICYCLIC PIPERIDINE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2015-05-28 | — | — | WO | claimed |