Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15854046 | 1.00 | LMNA (0.31) | LMNACYP2C9 | |
| SCHEMBL11993155 | 1.00 | LMNA (0.31) | LMNACYP2C9 | |
| SCHEMBL15468906 | 1.00 | LMNA (0.31) | LMNACYP2C9 | |
| SCHEMBL15468882 | 0.82 | — | — | |
| SCHEMBL15030963 | 0.82 | — | — | |
| SCHEMBL14232024 | 0.82 | — | — | |
| SCHEMBL20756547 | 0.79 | LMNA (0.42) | LMNACYP2C9 | |
| SCHEMBL16387221 | 0.79 | — | — | |
| SCHEMBL15440801 | 0.77 | SLC6A3 (0.37) | CYP2C9 | |
| SCHEMBL803421 | 0.77 | CYP2C9 (0.52) | LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598447-B2 | Phosphorus-substituted quinoxaline-type piperidine compounds and uses thereof | PURDUE PHARMA L.P. (US) | 2017-03-21 | — | — | US | disclosed |
| US-9040533-B2 | Oxime-substituted-quinoxaline-type piperidine compounds as ORL-1 modulators | PURDUE PHARMA L.P. (US) | 2015-05-26 | — | — | US | disclosed |