SCHEMBL4451311

SCHEMBL4451311

CO[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 12/20 0.56
PPARG P37231 10/20 0.56
PPARD Q03181 4/20 0.56
SLC7A5 Q01650 1/20 0.55
SRR Q9GZT4 4/20 0.51
ESR1 P03372 2/20 0.51
ESR2 Q92731 2/20 0.51
PSAT1 Q9Y617 2/20 0.50
LDHA P00338 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4941128 1.00 PPARA (0.56) PPARAPPARGPPARDSLC7A5SRR
SCHEMBL3466702 1.00 PPARA (0.56) PPARAPPARGPPARDSLC7A5SRR
SCHEMBL5607495 0.98 PPARA (0.55) PPARAPPARGPPARDSLC7A5SRR
SCHEMBL5607756 0.98 PPARA (0.55) PPARAPPARGPPARDSLC7A5SRR
Rubidium SCHEMBL5607497 0.98 PPARA (0.55) PPARAPPARGPPARDSLC7A5SRR
SCHEMBL5607096 0.98 PPARA (0.55) PPARAPPARGPPARDSLC7A5SRR
SCHEMBL5606722 0.98 PPARA (0.55) PPARAPPARGPPARDSLC7A5SRR
SCHEMBL4811729 0.98 PPARA (0.55) PPARAPPARGPPARDSLC7A5SRR
Ammonia Solution, Strong SCHEMBL5606748 0.98 PPARA (0.55) PPARAPPARGPPARDSLC7A5SRR
SCHEMBL5606989 0.98 PPARA (0.55) PPARAPPARGPPARDSLC7A5SRR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7427691-B2 Resolution of p-hydroxyphenyl-2-alkoxypropionic acids DEGUSSA GMBH (DE) 2008-09-23 US claimed
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
WO-2022078416-A1 NOVEL GLUTAMINE ANALOGS JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-04-21 WO disclosed
EP-1801093-B1 Process for the Preparation of enantiomer-enriched 2-Alkoxy-3-Phenyl-Propionic Acid SALTIGO GMBH (DE) 2009-03-18 EP disclosed
US-20090029429-A1 Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative KANEKA CORPORATION (JP) 2009-01-29 US disclosed
US-7429676-B2 Process for preparing enantiomerically enriched 2-alkoxy-3-phenylpropionic acids SALTIGO GMBH (DE) 2008-09-30 US disclosed
US-7429676-B2 Process for preparing enantiomerically enriched 2-alkoxy-3-phenylpropionic acids SALTIGO GMBH (DE) 2008-09-30 US disclosed
US-7427691-B2 Resolution of p-hydroxyphenyl-2-alkoxypropionic acids DEGUSSA GMBH (DE) 2008-09-23 US disclosed
US-20080064897-A1 Resolution of P-Hydroxyphenyl-2-Alkoxypropionic Acids GEGUSSA AG (DE) 2008-03-13 US disclosed
US-20060111406-A1 Amide linker peroxisome proliferator activated receptor modulators ELI LILLY AND COMPANY (US) 2006-05-25 US disclosed
WO-2006007976-A1 RESOLUTION OF P-HYDROXYPHENYL-2-ALKOXYPROPIONIC ACIDS DEGUSSA AG (DE) 2006-01-26 WO disclosed
CN-1662487-A Amide linker peroxisome proliferator-activated receptor modulators LILLY CO ELI (US) 2005-08-31 CN disclosed
EP-1517882-A1 AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-03-30 EP disclosed
US-20050020684-A1 Modulators of peroxisome proliferator activated receptors ELI LILLY AND COMPANY 2005-01-27 US disclosed
CN-1543451-A Receptor modulators activated by peroxizonal proliferators (ppar) 2004-11-03 CN disclosed
WO-2004000789-A9 AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS LILLY CO ELI (US) 2004-03-11 WO disclosed
EP-1392637-A2 MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ELI LILLY AND COMPANY (US) 2004-03-03 EP disclosed
WO-2004000789-A1 AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2003-12-31 WO disclosed
WO-2002100813-A2 MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ELI LILLY AND COMPANY (US) 2002-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399297-A1 Novel Glutamine Analogs GLUL, GATD3, GLS PPARA 1857/4885PPARG 1211/4885PPARD 1270/4885
US-20050020684-A1 Modulators of peroxisome proliferator activated receptors NCOA4, PPARG, PPARA PPARA 3/4885PPARG 2/4885PPARD 7/4885
US-20060111406-A1 Amide linker peroxisome proliferator activated receptor modulators PPARG, PPARA, PPARD PPARA 2/4885PPARG 1/4885PPARD 3/4885
US-20080064897-A1 Resolution of P-Hydroxyphenyl-2-Alkoxypropionic Acids PAH, GRHPR, NPPA PPARA 1931/4885PPARG 2184/4885PPARD 2162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.