Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3119793 | 0.95 | — | — | |
| SCHEMBL17079532 | 0.93 | TSHR (0.50) | TSHRALDH1A1THRBLPAR3ADORA1 | |
| SCHEMBL3122068 | 0.90 | — | — | |
| SCHEMBL16581580 | 0.89 | TSHR (0.43) | TSHRALDH1A1LPAR3ADORA1LMNA | |
| SCHEMBL18092837 | 0.89 | TSHR (0.43) | TSHRALDH1A1LPAR3ADORA1LMNA | |
| SCHEMBL3114132 | 0.88 | TSHR (0.54) | TSHRALDH1A1LPAR3ADORA1LMNA | |
| SCHEMBL3124662 | 0.88 | TSHR (0.54) | TSHRALDH1A1LPAR3ADORA1LMNA | |
| SCHEMBL3114287 | 0.88 | TSHR (0.54) | TSHRALDH1A1LPAR3ADORA1LMNA | |
| SCHEMBL12787211 | 0.88 | TSHR (0.52) | TSHRALDH1A1THRBADORA1LMNA | |
| SCHEMBL2528383 | 0.88 | TSHR (0.54) | TSHRALDH1A1LPAR3ADORA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148524-A1 | AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS | UNIV MONASH (AU) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148524-A1 | AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS | DAO, BCAT2, BCAT1 | TSHR 2676/4885ALDH1A1 3723/4885THRB 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.