SCHEMBL1674630

SCHEMBL1674630

CN(C)c1ccccc1CO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
MAPT P10636 2/20 0.45
ALDH1A1 P00352 2/20 0.45
TP53 P04637 1/20 0.45
TSHR P16473 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
AR P10275 1/20 0.44
CHEK1 O14757 1/20 0.43
NEK2 P51955 1/20 0.43
LIMK1 P53667 1/20 0.43
DYRK1A Q13627 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
APOBEC3G Q9HC16 1/20 0.43
EP300 Q09472 1/20 0.42
KAT2B Q92831 1/20 0.42
KAT8 Q9H7Z6 1/20 0.42
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
APP P05067 1/20 0.40
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4448098 0.86 APOBEC3G (0.43) GAAMAPTALDH1A1TP53TSHR
SCHEMBL249636 0.82 PTPN1 (0.47) GAAMAPTALDH1A1TP53TSHR
SCHEMBL8730306 0.81 MAPT (0.45) GAAMAPTALDH1A1TP53TSHR
SCHEMBL13486826 0.80 CHEK1 (0.48) GAAMAPTALDH1A1TSHRCHEK1
SCHEMBL308283 0.80 APOBEC3G (0.46) GAAALDH1A1TSHRAPOBEC3GPDCD1
SCHEMBL3871304 0.80 AR (0.50) GAAMAPTALDH1A1TP53TSHR
SCHEMBL29408555 0.80 AR (0.50) GAAMAPTALDH1A1TP53TSHR
SCHEMBL9802567 0.79 HSP90AA1 (0.44) TSHRAPOBEC3GPDCD1CD274
SCHEMBL8676051 0.79 GAA (0.39) GAAMAPTALDH1A1TP53TSHR
SCHEMBL4468365 0.79 GAA (0.39) GAAMAPTALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184520-A Biphenyl amine compound, preparation method thereof and application thereof in flow battery 中国科学院大连化学物理研究所 2024-06-14 CN claimed
CN-115369432-A Method for preparing nitrile by coupling electro-catalysis of primary alcohol and ammonia substances 大连理工大学 2022-11-22 CN claimed
CN-110396147-A The low temperature free radical polymerization of alkoxyamine ARKEMA FRANCE 2019-11-01 CN claimed
CN-102272133-A Modulators of amyloid beta 2011-12-07 CN claimed
US-20110189253-A1 BIOMATERIAL COMPOSITION AND METHOD WARSAW ORTHOPEDIC, INC. (US) 2011-08-04 US claimed
US-20060270750-A1 Bone cement compositions TA CONTRAST AB (SE) 2006-11-30 US claimed
EP-1610832-A2 BONE CEMENT COMPOSITIONS TA Contrast AB (SE) 2006-01-04 EP claimed
WO-2004087229-A2 BONE CEMENT COMPOSITIONS TA CONTRAST AB (SE) 2004-10-14 WO claimed
JP-62033139-A None JP disclosed
US-20250215144-A1 POLYMERIC ADHESIVE FOR ANCHORING COMPLIANT MATERIALS TO ANOTHER SURFACE CUSTOMERS BANK 2025-07-03 US disclosed
US-12139574-B2 Polymeric adhesive for anchoring compliant materials to another surface HYALEX ORTHOPAEDICS, INC. (US) 2024-11-12 US disclosed
CN-118184520-A Biphenyl amine compound, preparation method thereof and application thereof in flow battery 中国科学院大连化学物理研究所 2024-06-14 CN disclosed
CN-113785245-B Charge control agent and particle dispersion containing same 伊英克公司 2024-04-23 CN disclosed
US-20240076438-A1 POLYMERIC ADHESIVE FOR ANCHORING COMPLIANT MATERIALS TO ANOTHER SURFACE CUSTOMERS BANK 2024-03-07 US disclosed
WO-1991012000-A1 ANILINE DERIVATIVES OF α-STYRYL CARBINOLS AS ANTIFUNGAL AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-08-22 WO disclosed
US-5037830-A Antisecretory-antiulcer agents RICHTER GEDEON VEGYESZETI GYAR RT (HU) 1991-08-06 US disclosed
EP-0391254-A2 Novel thiouracil derivatives pharmaceutical compositions containing them and process for preparing same RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1990-10-10 EP disclosed
EP-0232399-A1 NEW AMINES, PROCESS FOR THEIR MANUFACTURE, THEIR USE AND MEDICINES CONTAINING THEM Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1987-08-19 EP disclosed
WO-1987001114-A2 NEW AMINES, PROCESS FOR THEIR MANUFACTURE, THEIR USE AND MEDICINES CONTAINING THEM BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1987-02-26 WO disclosed
JP-S6233139-A PRODUCTION OF 2-AMINOBENZYL ALCOHOL NIPPON CHEMIPHAR CO LTD 1987-02-13 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110189253-A1 BIOMATERIAL COMPOSITION AND METHOD ILK, KIT, CAD GAA 4159/4885MAPT 3969/4885ALDH1A1 1981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.