SCHEMBL1674762

SCHEMBL1674762

N[C@@H](CCC(=O)O)C(=O)OC(=O)CC[C@H](N)C(=O)OC(=O)[C@@H](N)CCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 2/20 0.54
GRM8 O00222 1/20 0.54
GRM6 O15303 1/20 0.54
GRIN2D O15399 1/20 0.54
GRIN3B O60391 1/20 0.54
GSR P00390 1/20 0.54
CYP1A2 P05177 1/20 0.54
GRIK1 P39086 1/20 0.54
GRM5 P41594 1/20 0.54
GRIA1 P42261 1/20 0.54
GRIA2 P42262 1/20 0.54
GRIA3 P42263 1/20 0.54
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
GRIA4 P48058 1/20 0.54
GRIN1 Q05586 1/20 0.54
GRIN2A Q12879 1/20 0.54
GRIK2 Q13002 1/20 0.54
GRIK3 Q13003 1/20 0.54
GRIN2B Q13224 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14125401 0.94 GRM8 (0.56) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL31206935 0.92 GRM8 (0.67) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL20508769 0.92 GRM8 (0.67) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL496858 0.92 GRM8 (0.62) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL4959221 0.92 GRM8 (0.62) SLC1A1GRM8GRM6GRIN2DGRIN3B
Glutamic Acid SCHEMBL27517274 0.91 GRM8 (0.64) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL7761327 0.90 SLC1A1 (0.47) SLC1A1GRM8GRM6GRIN2DGRIN3B
Hydrochloric Acid SCHEMBL10636419 0.90 GRM8 (0.60) SLC1A1GRM8GRM6GRIN2DGRIN3B
Glutamic Acid SCHEMBL27775331 0.89 GRM8 (0.62) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL1276948 0.89 SLC1A1 (0.41) SLC1A1GRM8GRM6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024190663-A1 BIOMARKER AND USE THEREOF 株式会社明治 2024-09-19 WO claimed
CN-117269494-A A group of metabolic markers for breast cancer lung metastasis 厦门大学 2023-12-22 CN claimed
CN-105683390-A HbA1c measurement method using amadoriase acting on glycated peptides 龟甲万株式会社 2016-06-15 CN claimed
EP-2661266-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES Elcelyx Therapeutics, Inc. (US) 2013-11-13 EP claimed
WO-2012094636-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES ELCELYX THERAPEUTICS, INC. (US) 2012-07-12 WO claimed
JP-H09510696-A 1997-10-28 JP claimed
EP-0737077-A1 HEPATOCYTE-TARGETED DRUG CONJUGATES TARGETECH, INC. (US) 1996-10-16 EP claimed
WO-1995018636-A2 HEPATOCYTE-TARGETED DRUG CONJUGATES TARGETECH INC (US) 1995-07-13 WO claimed
EP-3806661-B1 USE OF ANTAGONISTS OF T2R54 FIRMENICH INCORPORATED (US) 2025-07-02 EP disclosed
EP-4566459-A2 ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF Firmenich Incorporated (US) 2025-06-11 EP disclosed
US-12295396-B2 Antagonists of T2R54 and compositions and uses thereof FIRMENICH INCORPORATED (US) 2025-05-13 US disclosed
WO-2025072741-A1 PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO disclosed
CN-119639611-A Cryptosporidium-resistant synbiotic preparation and preparation method and application thereof 中国农业大学 2025-03-18 CN disclosed
CN-119257964-A Cleaning liquid capable of being washed-free or dry-cleaned and application thereof 苏州欧丽特生物医药有限公司 2025-01-07 CN disclosed
WO-2004012662-A2 IMPROVED TREATMENT OF CANCER WITH GLUTAMINE AESGEN, INC. (US) 2004-02-12 WO disclosed
US-20020147156-A1 Cellular uptake of bioactive agents EISAI INC. 2002-10-10 US disclosed
EP-1206283-A2 IMPROVED CELLULAR UPTAKE OF BIOACTIVE AGENTS Aesgen, Inc. (US) 2002-05-22 EP disclosed
WO-2000069470-A2 IMPROVED CELLULAR UPTAKE OF BIOACTIVE AGENTS AESGEN, INC. (US) 2000-11-23 WO disclosed
EP-0737077-A1 HEPATOCYTE-TARGETED DRUG CONJUGATES TARGETECH, INC. (US) 1996-10-16 EP disclosed
WO-1995018636-A2 HEPATOCYTE-TARGETED DRUG CONJUGATES TARGETECH INC (US) 1995-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12295396-B2 Antagonists of T2R54 and compositions and uses thereof TAS2R50, TAS2R30, TAS2R60 SLC1A1 476/4885GRM8 189/4885GRM6 112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.