SCHEMBL4959221

SCHEMBL4959221

N[C@@H](CCC(=O)O)C(=O)OC(=O)[C@@H](N)CCC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.62
GRM6 O15303 1/20 0.62
GRIN2D O15399 1/20 0.62
GRIN3B O60391 1/20 0.62
GSR P00390 1/20 0.62
CYP1A2 P05177 1/20 0.62
GRIK1 P39086 1/20 0.62
GRM5 P41594 1/20 0.62
GRIA1 P42261 1/20 0.62
GRIA2 P42262 1/20 0.62
GRIA3 P42263 1/20 0.62
SLC1A3 P43003 1/20 0.62
SLC1A2 P43004 1/20 0.62
SLC1A1 P43005 1/20 0.62
GRIA4 P48058 1/20 0.62
GRIN1 Q05586 1/20 0.62
GRIN2A Q12879 1/20 0.62
GRIK2 Q13002 1/20 0.62
GRIK3 Q13003 1/20 0.62
GRIN2B Q13224 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL496858 1.00 GRM8 (0.62) GRM8GRM6GRIN2DGRIN3BGSR
Hydrochloric Acid SCHEMBL10636419 0.98 GRM8 (0.60) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL3865479 0.92 GRM8 (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL29286626 0.92 GRM8 (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL3411544 0.92 BLM (0.57) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL29240009 0.92 BLM (0.57) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL1674762 0.92 SLC1A1 (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL2917215 0.91 GRM8 (0.58) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL435290 0.91 GRM8 (0.58) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL2801193 0.90 CYP1A2 (0.52) GRM8GRM6GRIN2DGRIN3BGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109467550-B Synthesis method of phthalic diamide-L-glutamic anhydride 苏州亚科科技股份有限公司 2022-02-18 CN claimed
US-20080026017-A1 Novel Dipeptides incorporating selenoamino acids with enhanced bioavailability- Synthesis, pharmaceutical and cosmeceutical applications thereof SAMI LABS LIMITED (IN) 2008-01-31 US claimed
CN-101044188-A Process for preparing glatiramer SANDOZ AG (CH) 2007-09-26 CN claimed
US-4600532-A Process and composition for amino-terminal, α-aspartyl and α-glutamyl dipeptides and dipeptide esters THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) 1986-07-15 US claimed
JP-56169597-A None JP disclosed
CN-113278548-B Lactobacillus crispatus and application thereof in producing products for improving human vaginal environment 南方医科大学珠江医院 2022-02-22 CN disclosed
CN-109467550-B Synthesis method of phthalic diamide-L-glutamic anhydride 苏州亚科科技股份有限公司 2022-02-18 CN disclosed
CN-109467550-B Synthesis method of phthalic diamide-L-glutamic anhydride 苏州亚科科技股份有限公司 2022-02-18 CN disclosed
CN-109467550-B Synthesis method of phthalic diamide-L-glutamic anhydride 苏州亚科科技股份有限公司 2022-02-18 CN disclosed
CN-108349877-B Novel citric acid derivatives 爱迪生物股份有限公司 2020-10-27 CN disclosed
CN-1986602-B Synthesis process of polyacrylamide-poly (L-glutamic acid)-benzyl ester graft copolymer UNIV LIAONING 2010-05-12 CN disclosed
CN-100509862-C Synthesis process of beta-cyclodextrin-poly-L-glutamic acid-benzyl ester grafted copolymer UNIV LIAONING (CN) 2009-07-08 CN disclosed
CN-1986602-A Synthesis process of polyacrylamide-poly (L-glutamic acid)-benzyl ester graft copolymer UNIV LIAONING (CN) 2007-06-27 CN disclosed
CN-1974605-A Synthesis process of beta-cyclodextrin-poly-L-glutamic acid-benzyl ester grafted copolymer UNIV LIAONING (CN) 2007-06-06 CN disclosed
JP-S56169597-A MEASUREMENT OF GAMMA-GLUTAMYL TRANS PEPTIDASE ACTIVITY EIKEN KAGAKU KK 1981-12-26 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080026017-A1 Novel Dipeptides incorporating selenoamino acids with enhanced bioavailability- Synthesis, pharmaceutical and cosmeceutical applications thereof SCLY, CYP2R1, SPR GRM8 1104/4885GRM6 807/4885GRIN2D 1965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.