SCHEMBL496858

SCHEMBL496858

NC(CCC(=O)O)C(=O)OC(=O)C(N)CCC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.62
GRM6 O15303 1/20 0.62
GRIN2D O15399 1/20 0.62
GRIN3B O60391 1/20 0.62
GSR P00390 1/20 0.62
CYP1A2 P05177 1/20 0.62
GRIK1 P39086 1/20 0.62
GRM5 P41594 1/20 0.62
GRIA1 P42261 1/20 0.62
GRIA2 P42262 1/20 0.62
GRIA3 P42263 1/20 0.62
SLC1A3 P43003 1/20 0.62
SLC1A2 P43004 1/20 0.62
SLC1A1 P43005 1/20 0.62
GRIA4 P48058 1/20 0.62
GRIN1 Q05586 1/20 0.62
GRIN2A Q12879 1/20 0.62
GRIK2 Q13002 1/20 0.62
GRIK3 Q13003 1/20 0.62
GRIN2B Q13224 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4959221 1.00 GRM8 (0.62) GRM8GRM6GRIN2DGRIN3BGSR
Hydrochloric Acid SCHEMBL10636419 0.98 GRM8 (0.60) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL3865479 0.92 GRM8 (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL29286626 0.92 GRM8 (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL3411544 0.92 BLM (0.57) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL29240009 0.92 BLM (0.57) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL1674762 0.92 SLC1A1 (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL2917215 0.91 GRM8 (0.58) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL435290 0.91 GRM8 (0.58) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL2801193 0.90 CYP1A2 (0.52) GRM8GRM6GRIN2DGRIN3BGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024190663-A1 BIOMARKER AND USE THEREOF 株式会社明治 2024-09-19 WO claimed
CN-117269494-A A group of metabolic markers for breast cancer lung metastasis 厦门大学 2023-12-22 CN claimed
CN-116507696-A Composition, method for producing same, and cosmetic 旭化成精细化工股份有限公司 2023-07-28 CN claimed
CN-116196294-A Amphiphilic polyamino acid drug-loaded nano-particle with stimulus responsiveness and preparation method thereof 宁德师范学院 2023-06-02 CN claimed
CN-115315477-A Thermoplastic starch composition, method for producing same, and use thereof 大象(株) 2022-11-08 CN claimed
CN-114524932-A Amphiphilic triblock polyamino acid copolymer, intermediate, preparation and application 宁德师范学院 2022-05-24 CN claimed
US-20050255160-A1 Polymide resin dermal composition SOHO LABORATORIES, INC. 2005-11-17 US claimed
US-5449743-A Enzymes as catalysts for ring opening polymerization of lactones, lactams, anhydrides or carbonates Kobayashi, Shiro (JP) 1995-09-12 US claimed
JP-8119916-A None JP disclosed
JP-11092259-A None JP disclosed
JP-55099072-A None JP disclosed
US-12630778-B2 Detergent-free and low-ash lubricating composition AFTON CHEMICAL CORPORATION (US) 2026-05-19 US disclosed
US-20260125612-A1 LUBRICATING FLUID FOR AN ELECTRIC MOTOR AFTON CHEMICAL CORP (US) 2026-05-07 US disclosed
EP-4737542-A1 LUBRICATING FLUID FOR AN ELECTRIC MOTOR Afton Chemical Corporation (US) 2026-05-06 EP disclosed
US-4600532-A Process and composition for amino-terminal, α-aspartyl and α-glutamyl dipeptides and dipeptide esters THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) 1986-07-15 US disclosed
US-4336331-A Method for assaying the activity of γ-glutamyl transpeptidase in serum NITTO BOSEKI CO., LTD. (JP) 1982-06-22 US disclosed
US-4326854-A EXTRUSION PRODUCT HAVING A COMBUSTIBLE BINDER TANNER JOHN D 1982-04-27 US disclosed
US-4281181-A SUBSTRATE FOR ASSAYING GLUTAMYL TRANSPEPTIDASE NITTO BOSEKI CO., LTD. (JP) 1981-07-28 US disclosed
JP-S5599072-A PRODUCTION OF ARTIFICIAL ANTIGEN CONTAINING CHOLINE RESIDUE MITSUBISHI PETROCHEM CO LTD 1980-07-28 JP disclosed
US-4138500-A HYDROLYSIS, ACYLATION KELLOGG COMPANY (US) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125612-A1 LUBRICATING FLUID FOR AN ELECTRIC MOTOR TST, AS3MT, SLC6A6 GRM8 1242/4885GRM6 121/4885GRIN2D 877/4885
US-12630778-B2 Detergent-free and low-ash lubricating composition SFN, PSPH, C9 GRM8 2925/4885GRM6 1277/4885GRIN2D 3179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.