Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001406 | 0.91 | LMNA (0.44) | LMNAALDH1A1TDP1CNR1ADRA1A | |
| SCHEMBL11004636 | 0.77 | LMNA (0.38) | LMNATDP1CNR1ADRA1AKDM4E | |
| SCHEMBL4606603 | 0.77 | TDP1 (0.47) | LMNAALDH1A1TDP1CNR1ADRA1A | |
| SCHEMBL25968487 | 0.77 | TDP1 (0.47) | LMNAALDH1A1TDP1CNR1ADRA1A | |
| SCHEMBL25968485 | 0.77 | TDP1 (0.47) | LMNAALDH1A1TDP1CNR1ADRA1A | |
| SCHEMBL4594420 | 0.77 | SLC22A6 (0.31) | — | |
| SCHEMBL19343054 | 0.73 | TSHR (0.44) | LMNATDP1CNR1ADRA1AKDM4E | |
| SCHEMBL19090720 | 0.73 | LMNA (0.48) | LMNAALDH1A1TDP1CNR1ADRA1A | |
| SCHEMBL13612890 | 0.73 | LMNA (0.48) | LMNAALDH1A1TDP1CNR1ADRA1A | |
| SCHEMBL20988048 | 0.73 | LMNA (0.48) | LMNAALDH1A1TDP1CNR1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424833-B1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES | ANGUS CHEMICAL (US) | 2015-07-29 | — | — | EP | claimed |
| US-8790456-B2 | Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies | ANGUS CHEMICAL COMPANY | 2014-07-29 | — | — | US | claimed |
| US-20140187820-A1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES | ANGUS CHEMICAL COMPANY (US) | 2014-07-03 | — | — | US | claimed |
| US-20140187678-A1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES | ANGUS CHEMICAL COMPANY (US) | 2014-07-03 | — | — | US | claimed |
| EP-2424833-A1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES | Dow Global Technologies LLC (US) | 2012-03-07 | — | — | EP | claimed |
| US-20120035298-A1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES | ADVANCION CORPORATION | 2012-02-09 | — | — | US | claimed |
| WO-2010126962-A1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-11-04 | — | — | WO | claimed |
| EP-2424833-B1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES | ANGUS CHEMICAL (US) | 2015-07-29 | — | — | EP | disclosed |
| US-8877979-B2 | Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-11-04 | — | — | US | disclosed |
| US-8790456-B2 | Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies | ANGUS CHEMICAL COMPANY | 2014-07-29 | — | — | US | disclosed |
| US-20140187820-A1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES | ANGUS CHEMICAL COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140187678-A1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES | ANGUS CHEMICAL COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
| US-8702859-B2 | Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-04-22 | — | — | US | disclosed |
| EP-2424833-A1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES | Dow Global Technologies LLC (US) | 2012-03-07 | — | — | EP | disclosed |
| US-20120035298-A1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES | ADVANCION CORPORATION | 2012-02-09 | — | — | US | disclosed |
| WO-2010126962-A1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035298-A1 | POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES | AOC1, DAO, DDO | LMNA 4259/4885ALDH1A1 72/4885TDP1 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.