Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510567 | 0.75 | HDAC8 (0.61) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL2510569 | 0.75 | HDAC8 (0.61) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL14791716 | 0.75 | HDAC1 (0.53) | HDAC8HDAC6HDAC1TUBB4ATUBB | |
| SCHEMBL16748457 | 0.75 | HDAC1 (0.61) | HDAC8HDAC6HDAC1TUBB4ATUBB | |
| SCHEMBL14106948 | 0.69 | HDAC8 (1.00) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL1306609 | 0.68 | MEN1 (0.64) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL1306613 | 0.68 | MEN1 (0.64) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL14609534 | 0.68 | TUBB4A (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2511476 | 0.65 | HDAC6 (0.59) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL1137630 | 0.65 | PARP1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763673-B1 | USE OF INDOLYL HYDROXAMATES FOR TREATING HEART FAILURE OR NEURONAL INJURY | UNIV TAIPEI MEDICAL (TW) | 2018-08-01 | — | — | EP | disclosed |
| WO-2015077685-A1 | USE OF INDOLYL AND IDOLINYL HYDROXAMATES FOR TREATING NEURODEGENERATIVE DISORDERS OR COGNITIVE DEFICITS | DCB-USA LLC (US) | 2015-05-28 | — | — | WO | disclosed |