Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23199851 | 0.96 | ALDH1A1 (0.47) | ALDH1A1ATMTSHRTDP1L3MBTL1 | |
| SCHEMBL16391280 | 0.94 | ALDH1A1 (0.45) | ALDH1A1ATMTSHRTDP1L3MBTL1 | |
| SCHEMBL18856346 | 0.89 | EPHX1 (0.50) | ALDH1A1TSHREPHX1ACHEHCAR2 | |
| SCHEMBL18487232 | 0.85 | TSHR (0.38) | ALDH1A1ATMTSHRTDP1L3MBTL1 | |
| SCHEMBL11172290 | 0.84 | GAA (0.38) | ALDH1A1TSHRTDP1LMNASMN1; SMN2 | |
| SCHEMBL1439148 | 0.84 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1HPGDHCAR2 | |
| SCHEMBL1439277 | 0.82 | CYP3A4 (0.40) | ALDH1A1TSHRTDP1HPGDHCAR2 | |
| SCHEMBL6058609 | 0.82 | ALDH1A1 (0.48) | ALDH1A1ATMTSHRTDP1L3MBTL1 | |
| SCHEMBL16711263 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ATMTSHRTDP1L3MBTL1 | |
| SCHEMBL17696810 | 0.81 | CNR2 (0.37) | ALDH1A1TSHRTDP1EPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160108016-A1 | Novel Cannabinergic Compounds and Uses Thereof | NORTHEASTERN UNIVERSITY (US) | 2016-04-21 | — | — | US | disclosed |
| EP-2646436-B1 | MONOBACTAMS | PFIZER (US) | 2015-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108016-A1 | Novel Cannabinergic Compounds and Uses Thereof | CNR2, CNR1, GPR18 | ALDH1A1 2810/4885ATM 1719/4885TSHR 1642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.