SCHEMBL1674897

SCHEMBL1674897

N#Cc1ccccc1/C=C/c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.50
TRPA1 O75762 2/20 0.50
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAOB P27338 3/20 0.41
MAOA P21397 2/20 0.41
PRKCQ Q04759 2/20 0.40
TSHR P16473 1/20 0.40
CYP19A1 P11511 1/20 0.40
NR1H3 Q13133 1/20 0.40
PRKCD Q05655 1/20 0.39
ATP4A P20648 2/20 0.39
ATP4B P51164 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29628296 1.00 NFE2L2 (0.50) NFE2L2TRPA1ALDH1A1HPGDALOX12
SCHEMBL1286236 1.00 NFE2L2 (0.50) NFE2L2TRPA1ALDH1A1HPGDALOX12
Benzene SCHEMBL29196105 1.00 NFE2L2 (0.50) NFE2L2TRPA1ALDH1A1HPGDALOX12
SCHEMBL11486051 0.98 NFE2L2 (0.48) NFE2L2TRPA1ALDH1A1HPGDALOX12
SCHEMBL11486049 0.98 NFE2L2 (0.48) NFE2L2TRPA1ALDH1A1HPGDALOX12
SCHEMBL29392092 0.94 NR1H3 (0.44) NFE2L2TRPA1TSHRNR1H3
SCHEMBL21574808 0.94 NR1H3 (0.44) NFE2L2TRPA1TSHRNR1H3
SCHEMBL553822 0.94 NR1H3 (0.44) NFE2L2TRPA1TSHRNR1H3
SCHEMBL553823 0.94 NR1H3 (0.44) NFE2L2TRPA1TSHRNR1H3
Butadiene SCHEMBL28426278 0.93 NFE2L2 (0.44) NFE2L2TRPA1ALDH1A1HPGDALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010779-A Chiral binaphthol-cyano stilbene compound and preparation method and application thereof 蚌埠学院 2026-05-12 CN claimed
US-12320774-B2 Macrocycle embedded organic electronic materials, composites, and compositions for chemical sensing NATIONAL SCIENCE FOUNDATION 2025-06-03 US claimed
CN-120058579-A Cyano stilbene derivative, preparation method thereof and application thereof in iodide ion detection 蚌埠学院 2025-05-30 CN claimed
CN-119874567-A Cyanostilbene derivative, preparation method thereof and application thereof in zinc ion recognition 常州大学 2025-04-25 CN claimed
CN-119462420-A Synthesis and application research of cyano stilbene derivative 淮南师范学院 2025-02-18 CN claimed
CN-118994289-B Alpha-cyano stilbene chiral fluorescent liquid crystal compound and preparation method thereof 苏州大学 2024-12-24 CN claimed
CN-118994289-A Alpha-cyano stilbene chiral fluorescent liquid crystal compound and preparation method thereof 苏州大学 2024-11-22 CN claimed
CN-118479983-A Synthesis method of cyano stilbene derivative organic compound 淮南师范学院 2024-08-13 CN claimed
WO-2024125945-A1 COMPOSITION FOR FORMING A LIQUID CRYSTAL ALIGNMENT FILM Rolic Technologies AG (CH) 2024-06-20 WO claimed
CN-110330589-B Light-responsive luminous liquid crystal elastomer material containing cyano-stilbene and preparation method thereof 湘潭大学 2024-04-26 CN claimed
WO-2018158254-A2 NEW PHOTOALIGNMENT COMPOSITION FOR THE STABILIZATION OF THE PRE-TILT ANGLE IN LIQUID CRYSTAL LAYERS Rolic Technologies AG (CH) 2018-09-07 WO claimed
US-20170313652-A1 Poly-Cyanostilbene Macrocycles NATIONAL SCIENCE FOUNDATION 2017-11-02 US claimed
US-9701621-B2 Poly-cyanostilbene macrocycles INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2017-07-11 US claimed
US-20150376122-A1 Poly-Cyanostilbene Macrocycles INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION 2015-12-31 US claimed
WO-2014127171-A1 POLY-CYANOSTILBENE MACROCYCLES INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2014-08-21 WO claimed
WO-2006115306-A1 NOVEL BRANCHED ALPHA-CYANOSTILBENE FLUOROPHORES PARK SOOYOUNG (KR) 2006-11-02 WO claimed
US-6534135-B1 Process of preparing discotic liquid crystalline compounds MERCK PATENT GESELLSCHAFT (DE) 2003-03-18 US claimed
EP-1066227-A1 PROCESS OF PREPARING DISCOTIC LIQUID CRYSTALLINE COMPOUNDS MERCK PATENT GmbH (DE) 2001-01-10 EP claimed
WO-1999048844-A1 PROCESS OF PREPARING DISCOTIC LIQUID CRYSTALLINE COMPOUNDS MERCK PATENT GMBH (DE) 1999-09-30 WO claimed
EP-0578327-A1 Non-linear optical waveguiding material comprising a dopant having multiple donor-pi-acceptor systems Akzo Nobel N.V. (NL) 1994-01-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150376122-A1 Poly-Cyanostilbene Macrocycles PCBP1, HCCS, ACVR2B NFE2L2 2519/4885TRPA1 2862/4885ALDH1A1 3023/4885
US-20170313652-A1 Poly-Cyanostilbene Macrocycles PCBP1, HCCS, ACVR2B NFE2L2 2519/4885TRPA1 2862/4885ALDH1A1 3023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.