SCHEMBL553822

SCHEMBL553822

N#Cc1ccccc1/C=C/c1ccc(/C=C/c2ccccc2C#N)cc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 1/20 0.44
NFE2L2 Q16236 8/20 0.44
TRPA1 O75762 2/20 0.42
TSHR P16473 1/20 0.41
LMNA P02545 1/20 0.40
RELA Q04206 2/20 0.38
FGF23 Q9GZV9 1/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP1B1 Q16678 1/20 0.38
APP P05067 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL553823 1.00 NR1H3 (0.44) NR1H3NFE2L2TRPA1TSHRLMNA
SCHEMBL29392092 1.00 NR1H3 (0.44) NR1H3NFE2L2TRPA1TSHRLMNA
SCHEMBL21574808 1.00 NR1H3 (0.44) NR1H3NFE2L2TRPA1TSHRLMNA
SCHEMBL11486051 0.96 NFE2L2 (0.48) NR1H3NFE2L2TRPA1RELA
SCHEMBL11486049 0.96 NFE2L2 (0.48) NR1H3NFE2L2TRPA1RELA
SCHEMBL11484561 0.94 NR1H3 (0.41) NR1H3NFE2L2TRPA1TSHRLMNA
SCHEMBL11484558 0.94 NR1H3 (0.41) NR1H3NFE2L2TRPA1TSHRLMNA
Benzene SCHEMBL29196105 0.94 NFE2L2 (0.50) NR1H3NFE2L2TRPA1TSHR
SCHEMBL1674897 0.94 NFE2L2 (0.50) NR1H3NFE2L2TRPA1TSHR
SCHEMBL29628296 0.94 NFE2L2 (0.50) NR1H3NFE2L2TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101120046-B Molded article exhibiting multi-color effects, associated lighting device and resin ARKEMA FRANCE 2011-02-23 CN claimed
US-20090129053-A1 LIGHT-ENHANCED ELEMENT LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. (TW) 2009-05-21 US claimed
US-20080214706-A1 Moulded Object Exhibiting a Polychromatic Effect, Associated Light Device and Resin ARKEMA FRANCE (FR) 2008-09-04 US claimed
EP-1848763-B1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN ARKEMA FRANCE (FR) 2008-04-16 EP claimed
CN-101120046-A Molded article exhibiting multi-color effects, associated lighting device and resin ARKEMA FRANCE (FR) 2008-02-06 CN claimed
EP-1848763-A1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN Arkema France (FR) 2007-10-31 EP claimed
US-20070159062-A1 Light-enhanced element LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. 2007-07-12 US claimed
WO-2006087241-A1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN ARKEMA FRANCE (FR) 2006-08-24 WO claimed
US-5152922-A 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1992-10-06 US claimed
EP-0240461-B1 MIXTURES OF OPTICAL BRIGHTENERS CIBA-GEIGY AG (CH) 1991-04-17 EP claimed
EP-0252009-B1 1,4-DISTYRYL BENZENE COMPOUNDS AND THEIR MIXTURES WITH OTHER 1,4-DISTYRYL BENZENE COMPOUNDS CIBA-GEIGY AG (CH) 1990-08-01 EP claimed
EP-0252009-A1 1,4-Distyryl benzene compounds and their mixtures with other 1,4-distyryl benzene compounds CIBA-GEIGY AG (CH) 1988-01-07 EP claimed
EP-0240461-A1 Mixtures of optical brighteners CIBA-GEIGY AG (CH) 1987-10-07 EP claimed
US-12303582-B2 Composition for the treatment of nail fungus OYSTERSHELL NV (BE) 2025-05-20 US disclosed
WO-2023126375-A1 MARKING COMPOSITION FOR APPLICATION ON A SPORTS PROJECTILE GROUNDTOUCH GMBH (DE) 2023-07-06 WO disclosed
CN-114108112-B Polyethylene sheet 江苏青昀新材料有限公司 2023-06-27 CN disclosed
EP-0003568-B1 COMPOSITION COMPRISING OPTICAL BRIGHTENING AGENTS FOR USE IN THE WHITENING OF PAPER COATING COMPOSITIONS BAYER AG (DE) 1982-06-02 EP disclosed
US-4283197-A Process for whitening polyester fibres by the exhaust method CIBA-GEIGY CORPORATION (US) 1981-08-11 US disclosed
EP-0017618-A1 Process for optically brightening polyester fibres by the exhaust process CIBA-GEIGY AG (CH) 1980-10-15 EP disclosed
EP-0003568-A1 Composition comprising optical brightening agents for use in the whitening of paper coating compositions BAYER AG (DE) 1979-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12303582-B2 Composition for the treatment of nail fungus DPM1, PIK3C3, ETF1 NR1H3 4446/4885NFE2L2 4280/4885TRPA1 648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.